P
Peter-Paul Zwetsloot
Researcher at Utrecht University
Publications - 15
Citations - 408
Peter-Paul Zwetsloot is an academic researcher from Utrecht University. The author has contributed to research in topics: Cardiac function curve & Extracorporeal membrane oxygenation. The author has an hindex of 7, co-authored 13 publications receiving 303 citations. Previous affiliations of Peter-Paul Zwetsloot include University Medical Center Utrecht.
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Journal ArticleDOI
Cardiac Stem Cell Treatment in Myocardial Infarction: A Systematic Review and Meta-Analysis of Preclinical Studies
Peter-Paul Zwetsloot,Anna M. D. Végh,Gerardus P.J. van Hout,Gillian L. Currie,Emily S. Sena,Hendrik Gremmels,Jan W. Buikema,Marie-José Goumans,Malcolm R. Macleod,Pieter A. Doevendans,Steven A. J. Chamuleau,Joost P.G. Sluijter +11 more
TL;DR: In this paper, the authors used meta-analysis to establish the overall effect of CSCs in preclinical studies and assessed translational differences between and within large and small animals in the CSC therapy field.
Journal ArticleDOI
Standardized mean differences cause funnel plot distortion in publication bias assessments
Peter-Paul Zwetsloot,Mira van der Naald,Emily S. Sena,David W. Howells,Joanna IntHout,Joris A. H. de Groot,Steven A. J. Chamuleau,Malcolm R. Macleod,Kimberley E. Wever +8 more
TL;DR: It is found that funnel plots of the Standardized Mean Difference plotted against the standard error (SE) are susceptible to distortion, leading to overestimation of the existence and extent of publication bias.
Journal ArticleDOI
Did a change in Nature journals’ editorial policy for life sciences research improve reporting?
Malcolm Macleod,Emily S. Sena,David J. Howells,Veronique Kiermer,Sowmya Swaminathan,Hugh Ash,Rosie Moreland,Cadi Irvine,Paula Grill,Monica Dingwall,Gillian L. Currie,Jing Liao,Chris Sena,Cilene Lino de Oliveira,Daniel-cosmin Marcu,Fala Cramond,Sulail Fatima Rajani,Andrew Ying,Hanna M. Vesterinen,Roncon Paolo,Kaitlyn Hair,Marie Soukupovà,Devon C. Crawford,Kimberley E. Wever,Mahajabeen Khatib,Ana Antonic,Thomas Ottavi,Xenios Milidonis,Klára Zsófia Gerlei,Thomas Barrett,Ye Liu,Chris H. Choi,Evandro Araújo De-Souza,Alexandra Bannach-Brown,Peter-Paul Zwetsloot,Kasper Jacobsen Kyng,Sarah K. McCann,Emily Wheater,Aaron Lawson McLean,Marco Casscella,Alice Carter,Privjyot Jheeta,Emma D. Eaton +42 more
TL;DR: There was an improvement in the reporting of risks of bias in in vivo research in NPG journals following a change in editorial policy, to a level that to the authors' knowledge has not been previously observed.
Journal ArticleDOI
Monocyte gene expression and coronary artery disease.
TL;DR: Recent findings indicate that genetic differences exist in circulating monocytes of patients suffering from CAD, giving more insights into the underlying mechanisms, however, larger studies are required to prove that monocytes’ expression signature could serve as a marker for diagnostic purposes in the future.
Journal ArticleDOI
Xenotransplantation of Human Cardiomyocyte Progenitor Cells Does Not Improve Cardiac Function in a Porcine Model of Chronic Ischemic Heart Failure. Results from a Randomized, Blinded, Placebo Controlled Trial.
Johannes M.I.H. Gho,Stefan Koudstaal,Gerardus P.J. van Hout,Peter-Paul Zwetsloot,Joep W. M. van Oorschot,Esther C M van Eeuwijk,Tim Leiner,Imo E. Hoefer,Marie-José Goumans,Pieter A. Doevendans,Joost P.G. Sluijter,Steven A. J. Chamuleau +11 more
TL;DR: Xenotransplantation via intracoronary infusion of hCMPCs is feasible and safe, but not associated with improved left ventricular performance and infarct size compared to placebo in a porcine model of chronic myocardial infarction.