P
Phil-Dong Moon
Researcher at Kyung Hee University
Publications - 102
Citations - 1783
Phil-Dong Moon is an academic researcher from Kyung Hee University. The author has contributed to research in topics: Tumor necrosis factor alpha & Thymic stromal lymphopoietin. The author has an hindex of 22, co-authored 93 publications receiving 1537 citations. Previous affiliations of Phil-Dong Moon include Wonkwang University & Hoseo University.
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Journal ArticleDOI
Use of scopoletin to inhibit the production of inflammatory cytokines through inhibition of the IκB/NF-κB signal cascade in the human mast cell line HMC-1
Phil-Dong Moon,Byung-Hee Lee,Hyun-Ja Jeong,Hyun-Ja Jeong,Hyo-Jin An,Seok-Jae Park,Hyung-Ryong Kim,Seong-Gyu Ko,Jae-Young Um,Seung-Heon Hong,Hyung-Min Kim +10 more
TL;DR: Results indicate that scopoletin has a potential regulatory effect on inflammatory reactions that are mediated by mast cells.
Journal ArticleDOI
Thymic stromal lymphopoietin is expressed and produced by caspase-1/NF-κB pathway in mast cells.
Phil-Dong Moon,Hyung-Min Kim +1 more
TL;DR: Results provide proof of principle that TSLP can be expressed and produced through caspase-1 and NF-κB in mast cells and open new perspectives to pharmacologically manipulate the expression and production of T SLP by molecules acting on the casp enzyme and NF -κB pathway.
Journal ArticleDOI
TSLP Induces Mast Cell Development and Aggravates Allergic Reactions through the Activation of MDM2 and STAT6
TL;DR: It is found that TSLP induced the proliferation and differentiation of mast cells from bone marrow progenitors and that it aggravates mast cell-mediated immune responses.
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The critical role of mast cell-derived hypoxia-inducible factor-1α in human and mice melanoma growth.
Hyun-Ja Jeong,Hyun-A Oh,Sun-Young Nam,Na-Ra Han,Young-Sick Kim,Jeong-Hwa Kim,Seok-Jong Lee,Min-Ho Kim,Phil-Dong Moon,Hyung-Min Kim +9 more
TL;DR: It is identified that the most positive cells for HIF‐1α staining are seen in mast cells of human and animal melanoma tissue and that the growth of melanoma can actually be exacerbated by mast cell‐derived HIF-1α.
Journal ArticleDOI
Green tea seed oil reduces weight gain in C57BL/6J mice and influences adipocyte differentiation by suppressing peroxisome proliferator-activated receptor-γ
Na-Hyung Kim,Sun-Kyung Choi,Su-Jin Kim,Phil-Dong Moon,Hun-Sun Lim,In-Young Choi,Ho-Jeong Na,Hyo-Jin An,Noh-Yil Myung,Hyun-Ja Jeong,Jae-Young Um,Seung-Heon Hong,Hyung-Min Kim +12 more
TL;DR: Results indicate that the anti-obesity effects of green tea seed oil might be, in part, through suppression of transcription factors related to adipocyte differentiation.