P
Philip C. Fox
Researcher at National Institutes of Health
Publications - 135
Citations - 8281
Philip C. Fox is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Salivary gland & Saliva. The author has an hindex of 52, co-authored 135 publications receiving 8014 citations. Previous affiliations of Philip C. Fox include Carolinas Medical Center.
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Subjective reports of xerostomia and objective measures of salivary gland performance
TL;DR: This study examines which questions are useful in identifying and predicting current major salivary gland output deficiency or dysfunction and collects saliva under unstimulated and stimulated conditions and asks standardized questions of 100 patients with xerostomia.
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Xerostomia: evaluation of a symptom with increasing significance
TL;DR: Xerostomia is the subjective sensation of oral dryness that is most commonly associated with salivary gland dysfunction, but it may also occur with normal gland activity.
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Clinical management of salivary gland hypofunction and xerostomia in head-and-neck cancer patients: successes and barriers
Arjan Vissink,James B. Mitchell,Bruce J. Baum,Kirsten H. Limesand,Siri Beier Jensen,Philip C. Fox,Linda S. Elting,Johannes A. Langendijk,Robert P. Coppes,Mary E. Reyland +9 more
TL;DR: This review addresses the pathophysiology underlying irradiation damage to salivary gland tissue, the consequences of radiation injury, and issues contributing to the clinical management of salivARY gland hypofunction and xerostomia.
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How Much Saliva is Enough
TL;DR: Results suggest that the comparison of major salivary gland flow rates of an individual with population standards to identify patients susceptible to the effects of Salivary dysfunction is unreliable.
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Major salivary gland function in patients with radiation- induced xerostomia: flow rates and sialochemistry
TL;DR: The SM/SL glands are clearly dysfunctional in post-irradiation xerostomia patients compared to controls, in terms of both flow rates and sialochemistry, which appears to be radiation dose- and field-dependent.