P
Philip D. Kanof
Researcher at Icahn School of Medicine at Mount Sinai
Publications - 34
Citations - 2408
Philip D. Kanof is an academic researcher from Icahn School of Medicine at Mount Sinai. The author has contributed to research in topics: Cholinergic & Nucleus basalis. The author has an hindex of 18, co-authored 34 publications receiving 2331 citations. Previous affiliations of Philip D. Kanof include Veterans Health Administration & United States Department of Veterans Affairs.
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Journal ArticleDOI
Neurochemical correlates of dementia severity in Alzheimer's disease: relative importance of the cholinergic deficits.
Linda M. Bierer,Vahram Haroutunian,S. Gabriel,P. Knott,Lorna S. Carlin,Dushyant P. Purohit,Daniel P. Perl,James Schmeidler,Philip D. Kanof,Kenneth L. Davis +9 more
TL;DR: It is suggested that of all the neurochemical species quantified, the cholinergic indices may be unique in their association with dementia severity, and none of the amines, their metabolites, or the neuropeptides quantified related significantly to dementia severity in the AD cohort.
Journal ArticleDOI
Two New Rating Scales for Opiate Withdrawal
Leonard Handelsman,Kenneth J. Cochrane,Marvin J. Aronson,Robert Ness,Karen J. Rubinstein,Philip D. Kanof +5 more
TL;DR: In this paper, two rating scales for measuring the signs and symptoms of opiate withdrawal are presented: Subjective Opiate Withdrawal Scale (SOWS) contains 16 symptoms whose intensity the patient rates on a scale of 0 (not at all) to 4 (extremely).
Two new rating scales for opiate withdrawal
Leonard Handelsman,Kenneth J. Cochrane,Marvin J. Aronson,Robert Ness,Karen J. Rubinstein,Philip D. Kanof +5 more
TL;DR: Good interrater reliability for the OOWS and good intrasubject reliability over time for both scales are demonstrated to be valid and reliable indicators of the severity of the opiate withdrawal syndrome over a wide range of common signs and symptoms.
Journal ArticleDOI
Pharmacological alleviation of cholinergic lesion induced memory deficits in rats
TL;DR: The hypothesis that central cholinergic systems are involved in the retention of learned responses in adult rats is supported, and the postacquisition administration of the acetylcholinesterase inhibitor, physostigmine, is suggested to be reversed.
Journal ArticleDOI
Restoration of cholinomimetic activity by clonidine in cholinergic plus noradrenergic lesioned rats.
Vahram Haroutunian,Vahram Haroutunian,Philip D. Kanof,Philip D. Kanof,G.K. Tsuboyama,G.K. Tsuboyama,Kenneth L. Davis,Kenneth L. Davis +7 more
TL;DR: Results suggest that combined cholinergic/noradrenergic therapy may be of value in the treatment of some Alzheimer's disease patients.