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Journal ArticleDOI

Two New Rating Scales for Opiate Withdrawal

TLDR
In this paper, two rating scales for measuring the signs and symptoms of opiate withdrawal are presented: Subjective Opiate Withdrawal Scale (SOWS) contains 16 symptoms whose intensity the patient rates on a scale of 0 (not at all) to 4 (extremely).
Abstract
Two new rating scales for measuring the signs and symptoms of opiate withdrawal are presented. The Subjective Opiate Withdrawal Scale (SOWS) contains 16 symptoms whose intensity the patient rates on a scale of 0 (not at all) to 4 (extremely). The Objective Opiate Withdrawal Scale (OOWS) contains 13 physically observable signs, rated present or absent, based on a timed period of observation of the patient by a rater. Opiate abusers admitted to a detoxification ward had significantly higher scores on the SOWS and OOWS before receiving methadone as compared to after receiving methadone for 2 days. Opiate abusers seeking treatment were challenged either with placebo or with 0.4 mg naloxone. Postchallenge SOWS and OOWS scores were significantly higher than prechallenge scores in the naloxone but not the placebo group. We have demonstrated good interrater reliability for the OOWS and good intrasubject reliability over time for both scales in controls and in patients on a methadone maintenance program. These scales are demonstrated to be valid and reliable indicators of the severity of the opiate withdrawal syndrome over a wide range of common signs and symptoms.

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Citations
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Journal ArticleDOI

The Clinical Opiate Withdrawal Scale (COWS)

TL;DR: The history of opiate withdrawal scales is reviewed and a template version of the COWS that can be copied and used clinically is appended.
Journal ArticleDOI

Opioids and the treatment of chronic pain: controversies, current status, and future directions.

TL;DR: A narrative review briefly describes the neurobiology of opioids and focuses on the complex issues at this interface between analgesia and abuse, including terminology, clinical challenges, and the potential for new agents, such as buprenorphine, to influence practice.
Journal ArticleDOI

Prevalence and Characteristics of Chronic Pain Among Chemically Dependent Patients in Methadone Maintenance and Residential Treatment Facilities

TL;DR: Chronic severe pain is prevalent among patients in substance abuse treatment, especially MMTP patients, and self-medication for pain with psychoactive drugs appears especially problematic among substance users who enroll in drug-free treatment programs.
Journal ArticleDOI

Opioid tolerance and hyperalgesia in chronic pain patients after one month of oral morphine therapy: a preliminary prospective study.

TL;DR: Experimental evidence suggests that opioid tolerance and opioid-induced hyperalgesia might limit the clinical utility of opioids in controlling chronic pain, but this study suggests that both conditions do occur within 1 month of initiating opioid therapy.

Guidelines for the Psychosocially Assisted Pharmacological Treatment of Opioid Dependence

TL;DR: The designations employed and the presentation of the material in this publication do not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries.
References
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Journal ArticleDOI

On the methods and theory of reliability.

TL;DR: This paper reviews the most frequently used and misused reliability measures appearing in the mental health literature and suggests some suitable reliability measures to be used.
Journal ArticleDOI

Clonidine blocks acute opiate-withdrawal symptoms

TL;DR: The data suggest that opiate withdrawal is due to increased neuronal activity in areas such as the locus coeruleus which are regulated by both alpha-2 adrenergic and opiate receptors.
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The clinical use of clonidine in abrupt withdrawal from methadone. Effects on blood pressure and specific signs and symptoms.

TL;DR: The withdrawal symptoms of anxiety, restlessness, insomnia, and muscular aching were most resistant to clonidine treatment and were reported by the majority of patients.
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