Philipp Schneider

TL;DR: An X-ray computed tomography technique that generates quantitative high-contrast three-dimensional electron density maps from phase contrast information without reverting to assumptions of a weak phase object or negligible absorption is described.

TL;DR: Results in two different mouse strains showed that the cannular and lacunar morphometry and their bone mechanics were fundamentally different.

TL;DR: This novel approach allows nondestructive 3D visualization and quantification of large microvascular networks, while retaining a precise anatomical context for ROIs scanned at very high resolution, opening new possibilities to study vessel architecture and vascular alterations in models of disease.

TL;DR: An imaging method is introduced that combines small-angle scattering with tensor tomography to probe nanoscale structures in three-dimensional macroscopic samples in a non-destructive way and allows, for example, the role of ultrastructure in the mechanical response of a biological tissue or manufactured material to be studied.

TL;DR: Different imaging methods regarding the quantitative 3D assessment of bone tissue in general and of the lacuno-canalicular network in particular will provide new insights in the field of bone mechanosensation and mechanotransduction and thus, into processes of strain sensation and transduction, which are tightly associated with osteocyte viability and bone quality.