scispace - formally typeset
P

Philippe Lesavre

Researcher at Necker-Enfants Malades Hospital

Publications -  89
Citations -  9129

Philippe Lesavre is an academic researcher from Necker-Enfants Malades Hospital. The author has contributed to research in topics: Proteinase 3 & Anti-neutrophil cytoplasmic antibody. The author has an hindex of 35, co-authored 89 publications receiving 8447 citations. Previous affiliations of Philippe Lesavre include University of Paris & Paris Descartes University.

Papers
More filters
Journal Article

Serum IgA preferentially binds to cationic polypeptides in IgA nephropathy.

Renato C. Monteiro, +3 more
- 01 Aug 1988 - 
TL;DR: When 18 patients with IgA-GN were tested after kidney transplantation, increased levels of cBSA-IgA and/or Ig a-RF were found to be associated with the recurrence of mesangial IgA deposits in the graft.
Journal ArticleDOI

Inhibition of matrix metalloproteinase-9 by interferons and TGF-β1 through distinct signalings accounts for reduced monocyte invasiveness

Juliette Nguyen, +3 more
- 24 Oct 2005 - 
TL;DR: The data point out the importance of IFNs and TGF‐β1 in the control of monocyte MMP‐9‐mediated extravasation.
Journal ArticleDOI

Characterization of a recombinant proteinase 3, the autoantigen in Wegener's granulomatosis and its reactivity with anti‐neutrophil cytoplasmic autoantibodies

Véronique Witko-Sarsat, +9 more
- 11 Mar 1996 - 
TL;DR: Improper disulfide bond formation and/or lack of post‐translational events in insect cells, may affect the conformation of PR3, precluding its reactivity with sera from WG patients.
Journal ArticleDOI

Isotype and affinity of anti-myeloperoxidase autoantibodies in systemic vasculitis.

Elisabeth Kokolina, +6 more
- 01 Jul 1994 - 
TL;DR: Anti-MPO IgG level increased during relapses but the affinity of these IgG autoantibodies remained low, and in a longitudinal study, high levels of anti-MPo IgM, when present, were observed early in the course of the disease and in some cases preceded the reappearance of pro-MPE IgG during relapse.
Journal ArticleDOI

Nonneoplastic circulating sézary‐like cells in cutaneous T‐cell lymphoma. Ultrastructural, immunologic, and T‐cell receptor gene‐rearrangement studies

Albert Bendelac, +7 more
- 01 Sep 1987 - 
TL;DR: It is concluded that reactive nonneoplastic Sézary‐like cells may be present not only in various benign conditions, as previously known, but also in T‐cell lymphomas.