P
Philippe Lesnik
Researcher at University of Paris
Publications - 75
Citations - 5766
Philippe Lesnik is an academic researcher from University of Paris. The author has contributed to research in topics: Cholesterol & Lipoprotein. The author has an hindex of 30, co-authored 72 publications receiving 4858 citations. Previous affiliations of Philippe Lesnik include Micalis Institute & National Institutes of Health.
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Journal ArticleDOI
Modulation of Gr1 low monocyte subset impacts insulin sensitivity and weight gain upon high-fat diet in female mice
Sophie Béliard,W. Le Goff,W. Le Goff,W. Le Goff,Flora Saint-Charles,Lucie Poupel,Virginie Deswaerte,L Bouchareychas,Thierry Huby,Thierry Huby,Thierry Huby,Philippe Lesnik,Philippe Lesnik,Philippe Lesnik +13 more
TL;DR: Evidence is established for a correlation between Gr1low monocyte subset and weight gain and RT, which could be used as a target for acting on AT inflammation and RT.
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Metabolic alterations, HFE gene mutations and atherogenic lipoprotein modifications in patients with primary iron overload.
Tomás Meroño,Tomás Meroño,Fernando Brites,Carolane Dauteuille,Marie Lhomme,Martín Menafra,Alejandra Arteaga,Marcelo Castro,María Soledad Saez,Esteban Gonzalez Ballerga,Patricia Sorroche,Jorge Rey,Philippe Lesnik,Juan Sordá,M. John Chapman,Anatol Kontush,Jorge Daruich +16 more
TL;DR: In this article, small, dense low-density lipoprotein (LDL) levels, chemical composition of LDL and HDL particles, and HDL functionality was assessed in primary iron overload (IO) patients.
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Reduced Reverse Cholesterol Transport Efficacy in Healthy Men with Undesirable Postprandial Triglyceride Response
Alexandre Motte Motte,Julie Gall,Joe-Elie Salem,Eric Dasque,Martine Lebot,Eric Frisdal,Sophie Galier,Elise F. Villard,Elodie Bouaziz-Amar,Jean-Marc Lacorte,Beny Charbit,Wilfried Le Goff,Philippe Lesnik,Maryse Guerin +13 more
TL;DR: Undesirable PP–TG response induces an overall reduction in RCT efficacy that contributes to the onset elevation of both fasting and nonfasting TG levels and to the development of cardiometabolic diseases.
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Haplotypes on pig chromosome 3 distinguish metabolically healthy from unhealthy obese individuals.
Simona Denise Frederiksen,Peter Karlskov-Mortensen,Sameer D. Pant,Maryse Guerin,Philippe Lesnik,Claus Jørgensen,Susanna Cirera,Camilla S. Bruun,Thomas Mark,Merete Fredholm +9 more
TL;DR: The genetic profile of the Göttingen Minipig breed seems to support a phenotype comparable to the metabolic healthy obese (MHO) phenotype in humans.
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Distinct Postprandial Bile Acids Responses to a High-Calorie Diet in Men Volunteers Underscore Metabolically Healthy and Unhealthy Phenotypes
Antonin Lamaziere,Dominique Rainteau,Pukar Kc,Lydie Humbert,Emilie Gauliard,Farid Ichou,Maharajah Ponnaiah,Nadine Bouby,Joe-Elie Salem,Jean-Maurice Mallet,Maryse Guerin,Philippe Lesnik +11 more
TL;DR: This study reveals that postprandial profiles/patterns of BAs in response to a hypercaloric high fat challenge is associated with healthy or unhealthy metabolic phenotypes that may help in the early identification of subjects at risk of developing metabolic disorders.