P
Phoebe A. Phillips
Researcher at University of New South Wales
Publications - 82
Citations - 6184
Phoebe A. Phillips is an academic researcher from University of New South Wales. The author has contributed to research in topics: Pancreatic cancer & Hepatic stellate cell. The author has an hindex of 34, co-authored 77 publications receiving 5321 citations. Previous affiliations of Phoebe A. Phillips include University of Western Sydney & University of Minnesota.
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Journal ArticleDOI
Desmoplastic reaction in pancreatic cancer: role of pancreatic stellate cells.
Minoti V. Apte,S Park,Phoebe A. Phillips,N. Santucci,David Goldstein,Rakesh K. Kumar,Grant A. Ramm,M.W. Büchler,Helmut Friess,Joshua A. McCarroll,Gregory W Keogh,Neil D. Merrett,Ron Pirola,Jeremy S. Wilson +13 more
TL;DR: Activated PSCs are present in theStromal reaction in pancreatic cancers and are responsible for the production of stromal collagen.
Journal ArticleDOI
Pancreatic Stellate Cells: Partners in Crime with Pancreatic Cancer Cells
Alain Vonlaufen,Swapna Joshi,Changfa Qu,Phoebe A. Phillips,Zhihong Xu,Nicole R. Parker,Cheryl S. Toi,Romano C. Pirola,Jeremy S. Wilson,David Goldstein,Minoti V. Apte +10 more
TL;DR: A significant interaction between pancreatic cancer cells and stromal cells (PSCs) is indicated and imply that pancreaticcancer cells recruit stronal cells to establish an environment that promotes cancer progression.
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StellaTUM: current consensus and discussion on pancreatic stellate cell research
Mert Erkan,Guido Adler,Minoti V. Apte,Max G. Bachem,Malte Buchholz,Sönke Detlefsen,Irene Esposito,Helmut Friess,Thomas M. Gress,Hans Joerg Habisch,Rosa F. Hwang,Robert Jaster,Jörg Kleeff,Günter Klöppel,Claus Kordes,Craig D. Logsdon,Atsushi Masamune,Christoph W. Michalski,Junseo Oh,Phoebe A. Phillips,Massimo Pinzani,Carolin Reiser-Erkan,Hidekazu Tsukamoto,Jeremy S. Wilson +23 more
TL;DR: Members of the Pancreatic Star Alliance discuss and consolidate current knowledge to outline and delineate areas of consensus or otherwise (eg, with regard to methodological approaches) and, more importantly, to identify essential directions for future research.
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Pancreatic stellate cells respond to inflammatory cytokines: potential role in chronic pancreatitis
P Mews,Phoebe A. Phillips,Roger G. Fahmy,Mark A. Korsten,Ron Pirola,Jeremy S. Wilson,Minoti V. Apte +6 more
TL;DR: This study has demonstrated that PSCs have the capacity to respond to cytokines known to be upregulated during acute pancreatitis, and may be a factor involved in the progression from acute pancitis to chronic pancreatic injury and fibrosis.
Journal ArticleDOI
Role of Pancreatic Stellate Cells in Pancreatic Cancer Metastasis
Zhihong Xu,Alain Vonlaufen,Phoebe A. Phillips,Eva Fiala-Beer,Xuguo Zhang,Lu Yang,Andrew V. Biankin,David Goldstein,Romano C. Pirola,Jeremy S. Wilson,Minoti V. Apte +10 more
TL;DR: Human PSCs accompany cancer cells to metastatic sites, stimulate angiogenesis, and are able to intravasate/extravasates to and from blood vessels.