P
Pierre Legrand
Researcher at Soleil Synchrotron
Publications - 140
Citations - 6683
Pierre Legrand is an academic researcher from Soleil Synchrotron. The author has contributed to research in topics: Infrared spectroscopy & Beamline. The author has an hindex of 39, co-authored 135 publications receiving 5845 citations. Previous affiliations of Pierre Legrand include French Institute of Health and Medical Research & Paul Sabatier University.
Papers
More filters
Journal ArticleDOI
Desulfovibrio desulfuricans iron hydrogenase: the structure shows unusual coordination to an active site Fe binuclear center.
TL;DR: The structure of the heterodimeric Fe-only hydrogenase from Desulfovibrio desulfuricans is reported - the first for this class of enzymes and it is suggested that it was imported from the inorganic world as an already functional unit.
Journal ArticleDOI
Isolation and characterisation of mesenchymal stem cells from adult mouse bone marrow
Philippe Tropel,Danièle Noël,Nadine Platet,Pierre Legrand,Alim-Louis Benabid,François Berger +5 more
TL;DR: Mouse MMSCs sharing the same morphological and functional characteristics as human MSCs can be successfully isolated from adult bone marrow without previous mouse or bone marrow treatment and it is demonstrated that this cell type after grafting in mouse pathology models has the MSC phenotype.
Journal ArticleDOI
Ni-Zn-[Fe4-S4] and Ni-Ni-[Fe4-S4] clusters in closed and open subunits of acetyl-CoA synthase/carbon monoxide dehydrogenase.
Claudine Darnault,Anne Volbeda,Eun Jin Kim,Pierre Legrand,X. Vernede,Paul A. Lindahl,Juan C. Fontecilla-Camps +6 more
TL;DR: It is postulate that only the A-clusters containing two Ni ions are catalytically active in the tetrameric α2β2 acetyl-coenzyme A synthase/carbon monoxide dehydrogenase from Moorella thermoacetica.
Journal ArticleDOI
Crystal structure of the 14-subunit RNA polymerase I
Carlos Fernández-Tornero,María Moreno-Morcillo,Umar Jan Rashid,Nicholas M.I. Taylor,Federico M. Ruiz,Tim Gruene,Pierre Legrand,Ulrich Steuerwald,Christoph W. Müller +8 more
TL;DR: The crystal structure of Pol I from Saccharomyces cerevisiae at 3.0 Å resolution shows a compact core with a wide DNA-binding cleft and a tightly anchored stalk, and an extended loop mimics the DNA backbone in the clefts and may be involved in regulating Pol I transcription.
Journal ArticleDOI
Structure and allosteric inhibition of excitatory amino acid transporter 1
Juan Carlos Canul-Tec,Reda Assal,Erica Cirri,Pierre Legrand,Sébastien Brier,Julia Chamot-Rooke,Nicolas Reyes +6 more
TL;DR: The first crystal structures of a thermostabilized human SLC1 transporter, the excitatory amino acid transporter 1 (EAAT1), with and without allosteric and competitive inhibitors bound are presented, showing novel architectural features of the human transporters.