P
Pierre M. Durand
Researcher at University of the Witwatersrand
Publications - 42
Citations - 1018
Pierre M. Durand is an academic researcher from University of the Witwatersrand. The author has contributed to research in topics: Multicellular organism & Genome. The author has an hindex of 18, co-authored 38 publications receiving 804 citations. Previous affiliations of Pierre M. Durand include National Health Laboratory Service & University of New Brunswick.
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On the paradigm of altruistic suicide in the unicellular world
TL;DR: It is argued that importing the paradigm of altruistic cell death from multicellular organisms to explain active death in unicellular lineages has the potential to limit the types of questions asked, thus biasing the understanding of the nature, origin, and maintenance of this trait.
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The Gonium pectorale genome demonstrates co-option of cell cycle regulation during the evolution of multicellularity
Erik R. Hanschen,Tara N. Marriage,Patrick J. Ferris,Takashi Hamaji,Atsushi Toyoda,Asao Fujiyama,Rafik Neme,Hideki Noguchi,Yohei Minakuchi,Masahiro Suzuki,Hiroko Kawai-Toyooka,David Roy Smith,Halle Sparks,Jaden Anderson,Robert Bakarić,Victor Luria,Victor Luria,Amir Karger,Marc W. Kirschner,Pierre M. Durand,Pierre M. Durand,Pierre M. Durand,Richard E. Michod,Richard E. Michod,Hisayoshi Nozaki,Bradley J. S. C. Olson,Bradley J. S. C. Olson +26 more
TL;DR: The genome sequence of the undifferentiated colonial alga, Gonium pectorale, is reported, where group formation evolved by co-option of the retinoblastoma cell cycle regulatory pathway, indicating extensive group-level adaptation during the initial step in the evolution of multicellularity.
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How an organism dies affects the fitness of its neighbors
TL;DR: To test whether PCD could be beneficial to nearby cells, induced programmed and nonprogrammed death in the unicellular green alga Chlamydomonas reinhardtii was induced and revealed that the beneficial effect of the PCD supernatant most likely involves simple heat-stable biomolecules.
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Programmed Cell Death and Complexity in Microbial Systems
TL;DR: It is concluded that PCD can increase biological complexity in microbial communities and is a means for solving a central problem of group living - the toxic effects of death - by making resources in dying cells beneficial to others.
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A role for programmed cell death in the microbial loop.
Mónica V. Orellana,Mónica V. Orellana,Wyming Lee Pang,Wyming Lee Pang,Pierre M. Durand,Pierre M. Durand,Kenia Whitehead,Nitin S. Baliga,Nitin S. Baliga +8 more
TL;DR: It is found that PCD in D. salina causes the release of organic nutrients such as glycerol, which can be used by others in the population as well as a co-occurring halophilic archaeon, which re-mineralizes the dissolved material promoting algal growth.