Pieter H. Reitsma

TL;DR: A recombinant protein S molecule is constructed that fails to bind C4BP and still displays cofactor activity for APC, and it is demonstrated that N-terminal residues 1-242 are sufficient for the expression of APC co Factor activity in a system using purified components.

TL;DR: The cloning of the human LACI gene is reported and the elucidation of its intron-exon organization is reported, which shows that the domain structure of other Kunitz-type protease inhibitors is reflected in the intron and exon organization of the gene.

TL;DR: This article found that individual differences in the quality of phonological representations play an important role in the development of explicit phonological awareness and reading acquisition in preschoolers. But, the results of the three longitudinal studies provided inconclusive support for the theory that individuals differences in their own phonological representation play a significant role in their reading development.

TL;DR: Using Southern blotting on probands of six unrelated families with hereditary protein S deficiency, one proband was found to have a grossly abnormal gene pattern, which agrees with the notion that hereditary thrombophilia associated withprotein S deficiency is indeed directly the result of a defect in the protein S gene.

TL;DR: The von Willebrand factor (vWF) genes of nine unrelated, severe, type III vonWillebrand's disease (vWD) patients and four unrelated Dutch type I vWD patients were screened for mutations in exons that contain CGA codons, which are liable to mutation to TGA stop codons.