P
Pirus Ghadjar
Researcher at Charité
Publications - 193
Citations - 4401
Pirus Ghadjar is an academic researcher from Charité. The author has contributed to research in topics: Radiation therapy & Prostate cancer. The author has an hindex of 33, co-authored 171 publications receiving 3528 citations. Previous affiliations of Pirus Ghadjar include Memorial Sloan Kettering Cancer Center & University Hospital of Bern.
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Journal ArticleDOI
Effect of Neoadjuvant Chemotherapy Plus Regional Hyperthermia on Long-term Outcomes Among Patients With Localized High-Risk Soft Tissue Sarcoma: The EORTC 62961-ESHO 95 Randomized Clinical Trial
Rolf D. Issels,Lars H. Lindner,Jaap Verweij,Rüdiger Wessalowski,Peter Reichardt,Peter Wust,Pirus Ghadjar,Peter Hohenberger,Martin K. Angele,Christoph Salat,Zeljko Vujaskovic,Soeren Daugaard,Olav Mella,Ulrich Mansmann,Hans Roland Dürr,Thomas Knösel,S. Abdel-Rahman,Michael Schmidt,Wolfgang Hiddemann,Karl-Walter Jauch,Claus Belka,Alessandro Gronchi +21 more
TL;DR: Among patients with localized high-risk soft tissue sarcoma the addition of regional hyperthermia to neoadjuvant chemotherapy resulted in increased survival, as well as local progression-free survival.
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Hyperthermia-related clinical trials on cancer treatment within the ClinicalTrials.gov registry.
Nikola Cihoric,Alexandros Tsikkinis,Gerard C. van Rhoon,Hans Crezee,Daniel M. Aebersold,Stephan Bodis,Marcus Beck,Jacek Nadobny,Volker Budach,Peter Wust,Pirus Ghadjar +10 more
TL;DR: This analysis summarises all recent clinical trials registered in the ClinicalTrials.gov registry and shows continuous interest and ongoing clinical research in the field of hyperthermia.
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Magnetic resonance thermometry: Methodology, pitfalls and practical solutions
Lukas Winter,Eva Oberacker,Katharina Paul,Yiyi Ji,Celal Oezerdem,Pirus Ghadjar,Alexander Thieme,Volker Budach,Peter Wust,Thoralf Niendorf +9 more
TL;DR: This review summarises and discusses advances in MR thermometry, providing practical considerations, pitfalls and technical obstacles constraining temperature measurement accuracy, spatial and temporal resolution in vivo.
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Comparative analysis of prostate-specific antigen free survival outcomes for patients with low, intermediate and high risk prostate cancer treatment by radical therapy. Results from the Prostate Cancer Results Study Group.
Pirus Ghadjar,George N. Thalmann +1 more
TL;DR: Results from other dose-escalation trials, meeting the inclusion criteria for the present analysis, were not included: The Medical Research Council RT01 trial reported a 5-year biochemical progression-free survival rate of 57% for 184 patients treated within the doseescalated arm after neoadjuvant ADT and the Dutch trial described a 6-year freedomfrom-failure rate of 49%, based on 179 patients from the experimental arm.
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The chemokine CCL20 and its receptor CCR6 in human malignancy with focus on colorectal cancer.
TL;DR: The literature on expression patterns of CCL20 and CCR6 and their physiological interactions as well as the currently presumed role of CCR 6 and CCL 20 in the formation of colorectal cancer liver metastasis are reviewed, providing a potential basis for novel treatment strategies.