P
Pnina Carmi
Researcher at Weizmann Institute of Science
Publications - 25
Citations - 1948
Pnina Carmi is an academic researcher from Weizmann Institute of Science. The author has contributed to research in topics: Heat shock protein & HSP60. The author has an hindex of 22, co-authored 25 publications receiving 1918 citations. Previous affiliations of Pnina Carmi include Brigham and Women's Hospital.
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Journal ArticleDOI
Heat Shock Protein 60 Activates B Cells via the TLR4-MyD88 Pathway
Michal Cohen-Sfady,Gabriel Nussbaum,Gabriel Nussbaum,Meirav Pevsner-Fischer,Felix Mor,Pnina Carmi,Alexandra Zanin-Zhorov,Ofer Lider,Irun R. Cohen +8 more
TL;DR: It is found that human HSP60 (but not the Escherichia coli GroEL or the Mycobacterial HSP65 molecules) induced naive mouse B cells to proliferate and to secrete IL-10 and IL-6.
Journal ArticleDOI
Hsp60 peptide therapy of NOD mouse diabetes induces a Th2 cytokine burst and downregulates autoimmunity to various beta-cell antigens.
Dana Elias,Aviram Meilin,Vitaly Ablamunits,Ohad S. Birk,Pnina Carmi,Stephanie Konen-Waisman,Irun R. Cohen +6 more
TL;DR: Effective peptide treatment of the diabetogenic process associated with the induction of antibodies may be explained by selective and transient activation of Th2 autoimmune reactivity.
Journal ArticleDOI
Purification of human tumor cell autocrine motility factor and molecular cloning of its receptor.
TL;DR: The motility stimulation of the fibrosarcoma cells with AMF is associated with the phosphorylation of the AMF receptor, a 78-kDa cell surface glycoprotein (gp78), suggesting protein kinase participation in migratory signal transduction.
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Evidence for the role of 34-kDa galactoside-binding lectin in transformation and metastasis.
Avraham Raz,Daguang Zhu,Victor Hogan,Nipa Shah,Tirza Raz,Rivka Karkash,Galit Pazerini,Pnina Carmi +7 more
TL;DR: Direct evidence is provided that the cellular expression of L‐34 is associated with some aspects of transformation and with metastasis, but not with tumorigenicity per se.
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Vaccination with Empty Plasmid DNA or CpG Oligonucleotide Inhibits Diabetes in Nonobese Diabetic Mice: Modulation of Spontaneous 60-kDa Heat Shock Protein Autoimmunity
TL;DR: It is reported that NOD diabetes can be inhibited by vaccination with a DNA construct encoding human HSP60, with the pcDNA3 empty vector, or with an oligonucleotide containing the CpG motif.