Prashant Jain

TL;DR: Chemical inhibition of either Arf6 or Epac blocks the effect of EF in cell culture and in vivo, opening new potential therapeutic avenues for treating symptoms caused by cAMP-inducing toxins or related barrier-disrupting pathologies.

TL;DR: From the Complex scoring and binding ability it is deciphered that these NCI diversity set II compounds could be promising inhibitors for Pseudomonas aeruginosa using AmpC /β ‐ lactamase as Drug target yet pharmacological studies have to confirm it.

TL;DR: A total of 12 cases of angiolipomas were received over a period of 2 years and comprised 13% of all lipomatous tumors and revealed fibrin thrombi in many capillaries, in all cases.

TL;DR: An overview of the synthesis, chemistry and applications of nanosystems carried out in our laboratory is presented in this article, where the discussion is divided into four sections, namely (a) chemistry of nanoparticles, (b) development of new synthetic approaches, (c) gas phase clusters and (d) device structures and applications.

TL;DR: This study has identified the important determinants or motif for substrate specificity of MAPK3/6 with six major transcription factors and found proline residue is present at +1 position of all phosphorylation sites that means proline might play an important role to enhance the binding affinity of MAPk3/ 6 with different transcription factors.