Q
Qian Li Xue
Researcher at Johns Hopkins University
Publications - 180
Citations - 13656
Qian Li Xue is an academic researcher from Johns Hopkins University. The author has contributed to research in topics: Medicine & Population. The author has an hindex of 52, co-authored 148 publications receiving 11328 citations. Previous affiliations of Qian Li Xue include University of Baltimore & Johns Hopkins University School of Medicine.
Papers
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Journal ArticleDOI
Hearing loss and cognitive decline in older adults
Frank R. Lin,Kristine Yaffe,Jin Xia,Qian Li Xue,Tamara B. Harris,Elizabeth Purchase-Helzner,Suzanne Satterfield,Hilsa N. Ayonayon,Luigi Ferrucci,Eleanor M. Simonsick +9 more
TL;DR: Hearing loss is independently associated with accelerated cognitive decline and incident cognitive impairment in community-dwelling older adults and the mechanistic basis of this association is and whether hearing rehabilitative interventions could affect cognitive decline is investigated.
Journal ArticleDOI
Phenotype of Frailty: Characterization in the Women's Health and Aging Studies
Karen Bandeen-Roche,Qian Li Xue,Luigi Ferrucci,Jeremy D. Walston,Jack M. Guralnik,Paulo H.M. Chaves,Scott L. Zeger,Linda P. Fried +7 more
TL;DR: The frailty definition developed in the CHS is applicable across diverse population samples and identifies a profile of high risk of multiple adverse outcomes and is consistent with the widely held theory that conceptualizes frailty as a syndrome.
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Frailty assessment instruments: Systematic characterization of the uses and contexts of highly-cited instruments.
Brian Buta,Jeremy D. Walston,Job G. Godino,Minsun Park,Rita R. Kalyani,Qian Li Xue,Karen Bandeen-Roche,Ravi Varadhan +7 more
TL;DR: Physical Frailty Phenotype was the most used frailty instrument in the research literature, followed by the Deficit Accumulation Index and the Vulnerable Elders Survey, and may be important to consider when selecting instruments for clinical or research purposes.
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Frailty in Older Adults: A Nationally Representative Profile in the United States
Karen Bandeen-Roche,Christopher L. Seplaki,Jin Huang,Brian Buta,Rita R. Kalyani,Ravi Varadhan,Qian Li Xue,Jeremy D. Walston,Judith D. Kasper +8 more
TL;DR: The findings support the importance of frailty in late-life health etiology and potential value of frailt as a marker of risk for adverse health outcomes and as a means of identifying opportunities for intervention in clinical practice and public health policy.
Journal ArticleDOI
Nonlinear Multisystem Physiological Dysregulation Associated With Frailty in Older Women: Implications for Etiology and Treatment
Linda P. Fried,Qian Li Xue,Anne R. Cappola,Luigi Ferrucci,Paulo H.M. Chaves,Ravi Varadhan,Jack M. Guralnik,Sean X. Leng,Richard D. Semba,Jeremy D. Walston,Caroline S. Blaum,Caroline S. Blaum,Karen Bandeen-Roche +12 more
TL;DR: It is shown that a threshold loss of complexity, as indicated by number of systems abnormal, may undermine homeostatic adaptive capacity, leading to the development of frailty and its associated risk for subsequent adverse outcomes.