R
Richard D. Semba
Researcher at Johns Hopkins University School of Medicine
Publications - 388
Citations - 20163
Richard D. Semba is an academic researcher from Johns Hopkins University School of Medicine. The author has contributed to research in topics: Population & Vitamin. The author has an hindex of 70, co-authored 380 publications receiving 17691 citations. Previous affiliations of Richard D. Semba include New York Academy of Medicine & Johns Hopkins University.
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Journal ArticleDOI
Low Nutrient Intake Is an Essential Component of Frailty in Older Persons
Benedetta Bartali,Edward A. Frongillo,Stefania Bandinelli,Fulvio Lauretani,Richard D. Semba,Linda P. Fried,Luigi Ferrucci +6 more
TL;DR: This study provides evidence that low intakes of energy and selected nutrients are independently associated with frailty.
Journal ArticleDOI
Nonlinear Multisystem Physiological Dysregulation Associated With Frailty in Older Women: Implications for Etiology and Treatment
Linda P. Fried,Qian Li Xue,Anne R. Cappola,Luigi Ferrucci,Paulo H.M. Chaves,Ravi Varadhan,Jack M. Guralnik,Sean X. Leng,Richard D. Semba,Jeremy D. Walston,Caroline S. Blaum,Caroline S. Blaum,Karen Bandeen-Roche +12 more
TL;DR: It is shown that a threshold loss of complexity, as indicated by number of systems abnormal, may undermine homeostatic adaptive capacity, leading to the development of frailty and its associated risk for subsequent adverse outcomes.
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Red Cell Distribution Width and Mortality in Older Adults: A Meta-analysis
Kushang V. Patel,Richard D. Semba,Luigi Ferrucci,Anne B. Newman,Linda P. Fried,Robert B. Wallace,Stefania Bandinelli,Caroline S. Phillips,Binbing Yu,Stephanie Connelly,Michael G. Shlipak,Paulo H.M. Chaves,Lenore J. Launer,William B. Ershler,Tamara B. Harris,Dan L. Longo,Jack M. Guralnik +16 more
TL;DR: RDW is a routinely reported test that is a powerful predictor of mortality in community-dwelling older adults with and without age-associated diseases and the biologic mechanisms underlying this association merit investigation.
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Does Accumulation of Advanced Glycation End Products Contribute to the Aging Phenotype
TL;DR: It is proposed that accumulation of AGEs accelerate the multisystem functional decline that occurs with aging, and therefore contribute to the aging phenotype.
Journal ArticleDOI
Human Immunodeficiency Virus Load in Breast Milk, Mastitis, and Mother-to-Child Transmission of Human Immunodeficiency Virus Type 1
Richard D. Semba,Newton Kumwenda,Donald R. Hoover,Taha E. Taha,Thomas C. Quinn,Thomas C. Quinn,Laban A.R. Mtimavalye,Robert J. Biggar,Robin L. Broadhead,Paolo G. Miotti,Lori J. Sokoll,Len van der Hoeven,John D. Chiphangwi +12 more
TL;DR: Mastitis and breast milk HIV-1 load may increase the risk of vertical transmission of HIV- 1 through breast-feeding.