Q
Qian Zhang
Researcher at Chinese Academy of Sciences
Publications - 13
Citations - 837
Qian Zhang is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: DNA origami & Targeted drug delivery. The author has an hindex of 7, co-authored 13 publications receiving 632 citations. Previous affiliations of Qian Zhang include Chinese Ministry of Education.
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Journal ArticleDOI
DNA Origami as an In Vivo Drug Delivery Vehicle for Cancer Therapy
Qian Zhang,Qiao Jiang,Na Li,Luru Dai,Qing Liu,Linlin Song,Jinye Wang,Yaqian Li,Jie Tian,Jie Tian,Baoquan Ding,Yang Du +11 more
TL;DR: It is demonstrated that DNA origami possessed enhanced tumor passive targeting and long-lasting properties at the tumor region and exhibited remarkable antitumor efficacy without observable systemic toxicity in nude mice bearing orthotopic breast tumors labeled with green fluorescent protein.
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A Self-Assembled DNA Origami-Gold Nanorod Complex for Cancer Theranostics
Qiao Jiang,Yuefeng Shi,Qian Zhang,Na Li,Pengfei Zhan,Linlin Song,Luru Dai,Jie Tian,Yang Du,Zhen Cheng,Baoquan Ding +10 more
TL;DR: The results demonstrate that the DO-GNR complex can achieve optimal two-photon cell imaging and photothermal effect, suggesting a promising candidate for cancer diagnosis and therapy both in vitro and in vivo.
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The Plasma Membrane-Localized Sucrose Transporter IbSWEET10 Contributes to the Resistance of Sweet Potato to Fusarium oxysporum.
TL;DR: This is the first report that the IbSWEET10 transporter contributes to the resistance of sweet potato to F. oxysporum, and it is suggested that the reduction in sugar content caused by IbS WEET10 overexpression is the major reason for the enhanced F.OxysporUM resistance of the transgenic plants.
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Transcript profile analysis reveals important roles of jasmonic acid signalling pathway in the response of sweet potato to salt stress.
TL;DR: It is revealed that the JA signalling pathway plays important roles in the response of sweet potato to salt stress, and insights are provided into the mechanisms and genes involved in the salt tolerance ofsweet potato.
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The enhanced chemotherapeutic effects of doxorubicin loaded PEG coated TiO2 nanocarriers in an orthotopic breast tumor bearing mouse model.
Yang Du,Wenzhi Ren,Yaqian Li,Yaqian Li,Qian Zhang,Leyong Zeng,Chongwei Chi,Aiguo Wu,Jie Tian +8 more
TL;DR: It was found that TiO2-PEG-DOX nanoparticles possessed improved antitumor efficacy without observable side effects compared to the free DOX treatment, and suggested that the PEG coatedTiO2 nanocarrier is a safe and potential platform for the efficient drug delivery and minimizing the systemic toxicity of chemotherapeutic agents.