Q
Qianqian Sun
Researcher at Harbin Engineering University
Publications - 23
Citations - 1374
Qianqian Sun is an academic researcher from Harbin Engineering University. The author has contributed to research in topics: Photothermal therapy & Photosensitizer. The author has an hindex of 13, co-authored 23 publications receiving 610 citations.
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Journal ArticleDOI
Hyaluronic acid-targeted and pH-responsive drug delivery system based on metal-organic frameworks for efficient antitumor therapy.
Qianqian Sun,Huiting Bi,Zhao Wang,Chunxia Li,Xuwei Wang,Jiating Xu,Hui Zhu,Ruoxi Zhao,Fei He,Shili Gai,Piaoping Yang +10 more
TL;DR: The study verified that HA shell, which could act as a smart "switch" and tumor-targeted "guider", had the capacity for extending blood circulation, enhancing the tumor-specific accumulation of DDS via CD44-mediated pathway.
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Fusiform-Like Copper(II)-Based Metal–Organic Framework through Relief Hypoxia and GSH-Depletion Co-Enhanced Starvation and Chemodynamic Synergetic Cancer Therapy
Zhao Wang,Bin Liu,Qianqian Sun,Shuming Dong,Ye Kuang,Yushan Dong,Fei He,Shili Gai,Piaoping Yang +8 more
TL;DR: Fusiform-like copper(II) based tetrakis (4-carboxy phenyl) porphyrin (TCPP) nanoscale metal-organic frameworks (nMOFs) facilitate the therapeutic efficiency of chemodynamic and starvation therapy via combination with relief hypoxia and GSH depletion after acting as an accurate imaging guide.
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Upconverted Metal-Organic Framework Janus Architecture for Near-Infrared and Ultrasound Co-Enhanced High Performance Tumor Therapy.
TL;DR: In this paper, a biocatalytic Janus nanocomposite (denoted as UPFB) was fabricated for ultrasound-driven sonodynamic therapy (SDT) and 808 nm near-infrared (NIR) light mediated PDT by combining core-shell-shell upconversion nanoparticles (UCNPs, NaYF4:20%Yb,1%Tm@NaYF 4:10%YB@NaNdF4) and a ferric zirconium porphyrin metal organic framework [PCN-
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Construction of Bi/phthalocyanine manganese nanocomposite for trimodal imaging directed photodynamic and photothermal therapy mediated by 808 nm light.
Zhao Wang,Tao Jia,Qianqian Sun,Ye Kuang,Bin Liu,Mengshu Xu,Hui Zhu,Fei He,Shili Gai,Piaoping Yang +9 more
TL;DR: In vivo fluorescence imaging vividly showed that the nanocomposite rapidly accumulates in tumor sites due to the enhanced permeability and retention (EPR) effect and metabolized in the organs, implying that the Nanocomposites have a high potential for use in imaging directed tumor therapy.
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Honeycomb-Satellite Structured pH/H2O2-Responsive Degradable Nanoplatform for Efficient Photodynamic Therapy and Multimodal Imaging
Qianqian Sun,Fei He,Chunqiang Sun,Xiangxi Wang,Chunxia Li,Jiating Xu,Dan Yang,Huiting Bi,Gai Shili,Piaoping Yang +9 more
TL;DR: The in vitro and in vivo experiments demonstrate that hMUC sample with the honeycomb-satellite structure can serve as multimodal bioimaging contrast agent for self-enhanced upconversion luminescence (UCL), magnetic resonance imaging (MRI) and computed tomography (CT) imaging, indicating that the as-prepared hM UC could be used in imaging-guided diagnosis and treatment.