R
R. Keith Slotkin
Researcher at Donald Danforth Plant Science Center
Publications - 74
Citations - 6395
R. Keith Slotkin is an academic researcher from Donald Danforth Plant Science Center. The author has contributed to research in topics: DNA methylation & Gene. The author has an hindex of 31, co-authored 66 publications receiving 5393 citations. Previous affiliations of R. Keith Slotkin include Ohio State University & University of California, Berkeley.
Papers
More filters
Journal ArticleDOI
Transposable elements and the epigenetic regulation of the genome.
TL;DR: New insights have been gained into how silencing in eukaryotic cells has been co-opted to serve essential functions in 'host' cells, highlighting the importance of TEs in the epigenetic regulation of the genome.
Journal ArticleDOI
Control of female gamete formation by a small RNA pathway in Arabidopsis
Vianey Olmedo-Monfil,Noé V. Durán-Figueroa,Mario A. Arteaga-Vazquez,Mario A. Arteaga-Vazquez,Edgar Demesa-Arevalo,Daphné Autran,Daniel Grimanelli,R. Keith Slotkin,R. Keith Slotkin,Robert A. Martienssen,Jean-Philippe Vielle-Calzada +10 more
TL;DR: The results show that AGO9-dependent sRNA silencing is crucial to specify cell fate in the Arabidopsis ovule, and that epigenetic reprogramming in companion cells is necessary for sRNA–dependent silencing in plant gametes.
Journal ArticleDOI
The Initiation of Epigenetic Silencing of Active Transposable Elements Is Triggered by RDR6 and 21-22 Nucleotide Small Interfering RNAs
Saivageethi Nuthikattu,Andrea D. McCue,Kaushik Panda,Dalen Fultz,Christopher DeFraia,Erica N. Thomas,R. Keith Slotkin +6 more
TL;DR: In this paper, the authors used a genome-wide search to identify transposable elements (TEs) that generate RDR6-dependent small interfering RNAs, and they used these TEs to test the function of RNA-dependent RNA-directed DNA methylation (RdDM) in assays for the de novo initiation, corrective reestablishment, and maintenance of TE silencing.
Journal ArticleDOI
Kismeth: Analyzer of plant methylation states through bisulfite sequencing
TL;DR: Kismeth simplifies bisulfite sequencing analysis, and is one of the few tools for the analysis of methylation patterns in plants, and facilitates analysis at both global and local scales.
Journal ArticleDOI
Non-canonical RNA-directed DNA methylation
TL;DR: This Review aims to illustrate the diversity of non-canonical RdDM mechanisms described to date, recognize common themes within this dizzying array of interconnected pathways, and identify the key unanswered questions remaining in this field.