R
Rachanee Udomsangpetch
Researcher at Mahidol University
Publications - 138
Citations - 6267
Rachanee Udomsangpetch is an academic researcher from Mahidol University. The author has contributed to research in topics: Plasmodium falciparum & Plasmodium vivax. The author has an hindex of 44, co-authored 137 publications receiving 5928 citations. Previous affiliations of Rachanee Udomsangpetch include John Radcliffe Hospital & Stockholm University.
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Journal ArticleDOI
Plasmodium falciparum-infected erythrocytes form spontaneous erythrocyte rosettes.
Rachanee Udomsangpetch,Birgitta Wahlin,Johan E. Carlson,Klavs Berzins,Motomi Torii,M. Aikawa,Peter Perlmann,Mats Wahlgren +7 more
TL;DR: The results indicate that cytoadherence of infected erythrocytes to endothelial cells and rosetting represent distinct genetic traits.
Journal ArticleDOI
Central Role of the Spleen in Malaria Parasite Clearance
Kesinee Chotivanich,Rachanee Udomsangpetch,Rose McGready,Stephane Proux,Paul N. Newton,Paul N. Newton,Sasithon Pukrittayakamee,Sornchai Looareesuwan,Nicholas J. White,Nicholas J. White +9 more
TL;DR: In a study of 5 patients with acute falciparum malaria who had previously undergone splenectomy, it was found that none of these 5 patients had any circulating RESA-RBCs, in contrast to the uniform finding of RESA, which confirms the central role of the spleen in the clearance of parasitized RBCs after antimalarial treatment with an artemisinin derivative.
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Wheat germ cell-free system-based production of malaria proteins for discovery of novel vaccine candidates.
Takafumi Tsuboi,Satoru Takeo,Hideyuki Iriko,Ling Jin,Masateru Tsuchimochi,Shusaku Matsuda,Eun-Taek Han,Hitoshi Otsuki,Osamu Kaneko,Jetsumon Sattabongkot,Rachanee Udomsangpetch,Tatsuya Sawasaki,Motomi Torii,Yaeta Endo +13 more
TL;DR: The wheat germ cell-free system can be used to produce malaria proteins without any prior optimization of their biased codon usage, indicating that this new cell- free system-based protocol for the discovery of malaria vaccine candidates will be discussed.
Journal ArticleDOI
Parasite Multiplication Potential and the Severity of Falciparum Malaria
Kesinee Chotivanich,Rachanee Udomsangpetch,Julie A. Simpson,Julie A. Simpson,Paul N. Newton,Paul N. Newton,Sasithon Pukrittayakamee,Sornchai Looareesuwan,Nicholas J. White,Nicholas J. White +9 more
TL;DR: P. falciparum parasites causing severe malaria were less selective and multiplied more at high parasitemias than those causing uncomplicated malaria.
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Plasmodium falciparum genome-wide scans for positive selection, recombination hot spots and resistance to antimalarial drugs
Jianbing Mu,Rachel A. Myers,Rachel A. Myers,Hongying Jiang,Shengfa Liu,Shengfa Liu,Stacy Ricklefs,Michael Waisberg,Kesinee Chotivanich,Polrat Wilairatana,Srivicha Krudsood,Nicholas J. White,Rachanee Udomsangpetch,Liwang Cui,May Ho,Fengzhen Ou,Haibo Li,Jianping Song,Guoqiao Li,Xinhua Wang,Suon Seila,Sreng Sokunthea,Duong Socheat,Daniel E. Sturdevant,Stephen F. Porcella,Rick M. Fairhurst,Thomas E. Wellems,Philip Awadalla,Xin-zhuan Su +28 more
TL;DR: This is the first Plasmodium GWAS, which included 189 culture-adapted P. falciparum parasites genotyped using a custom-built Affymetrix molecular inversion probe 3K malaria panel array with a coverage of ∼1 SNP per 7 kb and detected population structure, variation in recombination rate and loci under recent positive selection.