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Rachel C. Bandler
Researcher at New York University
Publications - 12
Citations - 1285
Rachel C. Bandler is an academic researcher from New York University. The author has contributed to research in topics: Interneuron & Population. The author has an hindex of 7, co-authored 10 publications receiving 977 citations. Previous affiliations of Rachel C. Bandler include Broad Institute & Massachusetts Institute of Technology.
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Journal ArticleDOI
Noninvasive optical inhibition with a red-shifted microbial rhodopsin
Amy S. Chuong,Mitra L Miri,Volker Busskamp,Gillian A. Matthews,Leah Acker,Andreas T. Sørensen,Andrew Young,Nathan C. Klapoetke,Henninger Michael,Suhasa B. Kodandaramaiah,Masaaki Ogawa,Shreshtha B. Ramanlal,Rachel C. Bandler,Brian D. Allen,Craig R. Forest,Brian Y. Chow,Xue Han,Yingxi Lin,Kay M. Tye,Botond Roska,Jessica A. Cardin,Edward S. Boyden +21 more
TL;DR: The red-shifted cruxhalorhodopsin, Jaws, derived from Haloarcula (Halobacterium) salinarum (strain Shark) and engineered to result in red light–induced photocurrents three times those of earlier silencers is presented, offering a powerful general-use chloride pump for basic and applied neuroscience.
Journal ArticleDOI
Developmental diversification of cortical inhibitory interneurons.
Christian Mayer,Christoph Hafemeister,Rachel C. Bandler,Robert Machold,Renata Batista Brito,Xavier H. Jaglin,Xavier H. Jaglin,Kathryn C. Allaway,Kathryn C. Allaway,Andrew Butler,Gord Fishell,Rahul Satija +11 more
TL;DR: The authors' analysis revealed that the transcription factor Mef2c delineates early precursors of parvalbumin-expressing neurons, and is essential for their development, and uncovered the embryonic emergence of cardinal interneuron subtypes.
Journal ArticleDOI
microRNA-33 Regulates Macrophage Autophagy in Atherosclerosis.
Mireille Ouimet,Hasini Ediriweera,Milessa Silva Afonso,Bhama Ramkhelawon,Ragunath Singaravelu,Xianghai Liao,Rachel C. Bandler,Karishma Rahman,Edward A. Fisher,Katey J. Rayner,John Paul Pezacki,Ira Tabas,Kathryn J. Moore +12 more
TL;DR: It is shown that treating atherosclerotic Ldlr−/− mice with anti-miR-33 restores defective autophagy in macrophage foam cells and plaques and promotes apoptotic cell clearance to reduce plaque necrosis, providing insight into the mechanisms by which miR- 33 regulates cellular cholesterol homeostasis and atherosclerosis.
Journal ArticleDOI
Clonally Related Forebrain Interneurons Disperse Broadly across Both Functional Areas and Structural Boundaries
Christian Mayer,Xavier H. Jaglin,Lucy Cobbs,Rachel C. Bandler,Carmen Streicher,Constance L. Cepko,Simon Hippenmeyer,Gord Fishell +7 more
TL;DR: The findings uncover that lineage relationships do not appear to determine interneuron allocation to particular regions, and it is likely that clonally related interneurons have considerable flexibility as to the particular forebrain circuits to which they can contribute.
Journal ArticleDOI
Cortical interneuron specification: the juncture of genes, time and geometry.
TL;DR: This review will cover recent work that has advanced knowledge of the mechanisms governing cortical interneuron subtype specification, particularly progenitors' spatial origin, birthdates, lineage, and mode of division.