Rachel J. Rybak

TL;DR: In this article, a group of young female rats were cycled through a restriction period (4 days of 66% of control food intake) followed by 6 days of free feeding prior to being stressed by acute foot shock.

TL;DR: In this article, the authors developed an animal model of binge eating in sated rats that is evoked by stress, but only in rats with a history of caloric restriction and only if highly palatable food (HPF) is available after stress.

TL;DR: A number of new nucleoside analogues with a Z- or E-methylenecyclopropane structure exhibited significant activity against human and murine cytomegaloviruses (HCMV, MCV) in tissue culture that was generally comparable to, or greater than, 9-[(1-3-dihydroxy-2-propoxy)methyl]guanine (ganciclovir, GCV).

TL;DR: Results indicate that both the SCID-hu retinal and SCid-hu thy/liv implant models are useful for determining in vivo activity against HCMV, and appear to be predictive of efficacy for both ocular and systemic infections in humans.

TL;DR: 1-O-hexadecylpropanediol-3–P-acyclovir, an orally bioavailable lipid prodrug of acyclovirs evaluated it for in vitro and in vivo activity against herpes simplex virus infections and had somewhat higher activity in cytomegalovirus infection in vitro.