P
P. C. Chandler
Researcher at University of Alabama at Birmingham
Publications - 11
Citations - 886
P. C. Chandler is an academic researcher from University of Alabama at Birmingham. The author has contributed to research in topics: Binge eating & Eating disorders. The author has an hindex of 10, co-authored 11 publications receiving 860 citations.
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A new animal model of binge eating: Key synergistic role of past caloric restriction and stress
TL;DR: In this article, a group of young female rats were cycled through a restriction period (4 days of 66% of control food intake) followed by 6 days of free feeding prior to being stressed by acute foot shock.
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The role of palatable food and hunger as trigger factors in an animal model of stress induced binge eating.
TL;DR: In this article, the authors developed an animal model of binge eating in sated rats that is evoked by stress, but only in rats with a history of caloric restriction and only if highly palatable food (HPF) is available after stress.
Journal ArticleDOI
PYY3-36 as an anti-obesity drug target.
Mary M. Boggiano,P. C. Chandler,Kimberly D. Oswald,R.J. Rodgers,John E. Blundell,Y. Ishii,A. H. Beattie,Patricia Holch,David B. Allison,Marcus Schindler,Kirsten Arndt,Klaus Rudolf,M. Mark,C. Schoelch,H. G. Joost,Susanne Klaus,Christa Thöne-Reineke,Stephen C. Benoit,Randy J. Seeley,Annette G. Beck-Sickinger,Norman Koglin,Kirsten Raun,Kjeld Madsen,Birgitte Schjellerup Wulff,Carsten Enggaard Stidsen,Marc Birringer,Oliver J. Kreuzer,X. Y. Deng,D. C. Whitcomb,Heather A. Halem,John E. Taylor,Jesse Z. Dong,Rakesh Datta,Michael D. Culler,Sylvia Ortmann,Tamara R. Castañeda,M.H. Tschöp +36 more
TL;DR: Data speak against a sustained decrease in food intake, body fat, or body weight gain following PYY3‐36 administration and make the previously suggested role of the hypothalamic melanocortin system unlikely as is the existence of PYY deficiency in human obesity.
Journal ArticleDOI
Combined dieting and stress evoke exaggerated responses to opioids in binge-eating rats.
Mary M. Boggiano,P. C. Chandler,Jason B. Viana,Kimberly D. Oswald,Christine R. Maldonado,P.K Wauford +5 more
TL;DR: Although butorphanol did not trigger chow binge eating, it enhanced binge eating of palatable food, which strengthens evidence that reward, over metabolic need, drives binge eating.
Journal ArticleDOI
Erratum: Does gut hormone PVY3-36 decrease food intake in rodents? (Nature (2004) 430 (165) DOI:10.1038/nature03019)
M.H. Tschöp,Tamara R. Castañeda,H. G. Joost,Christa Thöne-Reineke,S. Ortmam,Susanne Klaus,Mary M. Hagan,P. C. Chandler,Kimberly D. Oswald,Stephen C. Benoit,Randy J. Seeley,K. P. Kinzig,T. H. Moran,Annette G. Beck-Sickinger,Norman Koglin,R.J. Rodgers,John E. Blundell,Y. Ishii,A. H. Beattie,Patricia Holch,David B. Allison,Kirsten Raun,Kjeld Madsen,Birgitte Schjellerup Wulff,Carsten Enggaard Stidsen,Marc Birringer,O. J. Kreuzer,Marcus Schindler,Kirsten Arndt,Klaus Rudolf,M. Mark,Xiaolan Deng,D. C. Withcomb,Heather A. Halem,John Taylor,J. Dong,Rakesh Datta,Michael D. Culler,S. Craney,D. Flora,David L. Smiley,Mark L. Heiman +41 more