Rachel M. Warga

TL;DR: It is shown that beta-catenin, acting as a component of the wnt-pathway, transiently accumulates in nuclei on the dorsal side of Xenopus and zebrafish blastulae and is an early step in the establishment of the dorsal-ventral axis in frog and fish embryos.

TL;DR: In this paper, two groups of mutants with defects in this patterning process have been isolated in a screen for zygotic mutations affecting the embryonic development of the zebrafish (Danio rerio).

TL;DR: Comparison of their phenotypes permits classification of these mutations according to the types of defects they cause, and these suggest which process of neural crest development is probably affected, as part of a large-scale mutagenesis screen for embryonic/early larval mutations.

TL;DR: In cyclops-mutant embryos that have reduced mesodermal anlage, it is demonstrated that by late gastrulation not only mesodmal but also endodermal cells are fewer in number, suggesting that a common pathway initially specifies germ layers together before a progressive sequence of determinative events segregate endoderm and mesoderm into morphologically distinct germ layers.

TL;DR: The phenotypes suggests that dino and mercedes are required for the establishment of dorsal fates in both the marginal and the animal zone of the early gastrula embryo.