C
Carl-Philipp Heisenberg
Researcher at Institute of Science and Technology Austria
Publications - 178
Citations - 23816
Carl-Philipp Heisenberg is an academic researcher from Institute of Science and Technology Austria. The author has contributed to research in topics: Zebrafish & Gastrulation. The author has an hindex of 74, co-authored 167 publications receiving 21469 citations. Previous affiliations of Carl-Philipp Heisenberg include Life Sciences Institute & Cancer Research UK.
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The identification of genes with unique and essential functions in the development of the zebrafish, Danio rerio
P. Haffter,Michael Granato,Michael Brand,Mary C. Mullins,M. Hammerschmidt,D. A. Kane,J. Odenthal,F. J. M. Van Eeden,Y.-J. Jiang,Carl-Philipp Heisenberg,Robert N. Kelsh,Makoto Furutani-Seiki,Elisabeth Vogelsang,D. Beuchle,U. Schach,C. Fabian,Christiane Nüsslein-Volhard +16 more
TL;DR: It is estimated that the 372 genes defined by the mutants probably represent more than half of all genes that could have been discovered using the criteria of the screen, and the limits and the potentials of a genetic saturation screen in the zebrafish.
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Silberblick/Wnt11 mediates convergent extension movements during zebrafish gastrulation.
Carl-Philipp Heisenberg,Masazumi Tada,Gerd-Jörg Rauch,Leonor Saúde,Miguel L. Concha,Robert Geisler,Derek L. Stemple,James C. Smith,Stephen W. Wilson +8 more
TL;DR: It is shown that the zebrafish silberblick locus encodes Wnt11 and that Slb/Wnt11 activity is required for cells to undergo correct convergent extension movements during gastrulation, and that the correct extension of axial tissue is at least partly dependent on medio-lateral cell intercalation in paraxial tissue.
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Forces in Tissue Morphogenesis and Patterning
TL;DR: The interplay between tissue mechanics and biochemical signaling orchestrates tissue morphogenesis and patterning in development.
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Tensile forces govern germ-layer organization in zebrafish
Michael Krieg,Y. Arboleda-Estudillo,Y. Arboleda-Estudillo,Pierre-Henri Puech,Jos Käfer,François Graner,Daniel J. Müller,Carl-Philipp Heisenberg +7 more
TL;DR: It is shown that differential actomyosin-dependent cell-cortex tension, regulated by Nodal/TGFβ-signalling (transforming growth factor β), constitutes a key factor that directs progenitor-cell sorting in germ-layer organization during gastrulation.
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Genes controlling and mediating locomotion behavior of the zebrafish embryo and larva
Michael Granato,F. J. M. Van Eeden,U. Schach,T. Trowe,Michael Brand,Makoto Furutani-Seiki,P. Haffter,M. Hammerschmidt,Carl-Philipp Heisenberg,Y.-J. Jiang,D. A. Kane,Robert N. Kelsh,Mary C. Mullins,J. Odenthal,Christiane Nüsslein-Volhard +14 more
TL;DR: Analysis of the behavioral defects suggests that these genes participate in the diverse locomotion patterns observed, such as touch response, rhythmic tail movements, equilibrium control, or that they simply confer general motility to the animal.