M
Michael Granato
Researcher at University of Pennsylvania
Publications - 128
Citations - 14418
Michael Granato is an academic researcher from University of Pennsylvania. The author has contributed to research in topics: Zebrafish & Gene. The author has an hindex of 58, co-authored 117 publications receiving 13462 citations. Previous affiliations of Michael Granato include Cancer Research UK & Max Planck Society.
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Journal ArticleDOI
The identification of genes with unique and essential functions in the development of the zebrafish, Danio rerio
P. Haffter,Michael Granato,Michael Brand,Mary C. Mullins,M. Hammerschmidt,D. A. Kane,J. Odenthal,F. J. M. Van Eeden,Y.-J. Jiang,Carl-Philipp Heisenberg,Robert N. Kelsh,Makoto Furutani-Seiki,Elisabeth Vogelsang,D. Beuchle,U. Schach,C. Fabian,Christiane Nüsslein-Volhard +16 more
TL;DR: It is estimated that the 372 genes defined by the mutants probably represent more than half of all genes that could have been discovered using the criteria of the screen, and the limits and the potentials of a genetic saturation screen in the zebrafish.
Journal ArticleDOI
Genes controlling and mediating locomotion behavior of the zebrafish embryo and larva
Michael Granato,F. J. M. Van Eeden,U. Schach,T. Trowe,Michael Brand,Makoto Furutani-Seiki,P. Haffter,M. Hammerschmidt,Carl-Philipp Heisenberg,Y.-J. Jiang,D. A. Kane,Robert N. Kelsh,Mary C. Mullins,J. Odenthal,Christiane Nüsslein-Volhard +14 more
TL;DR: Analysis of the behavioral defects suggests that these genes participate in the diverse locomotion patterns observed, such as touch response, rhythmic tail movements, equilibrium control, or that they simply confer general motility to the animal.
Journal ArticleDOI
Mutations affecting somite formation and patterning in the zebrafish, Danio rerio
F. J. M. Van Eeden,Michael Granato,U. Schach,Michael Brand,Makoto Furutani-Seiki,P. Haffter,M. Hammerschmidt,Carl-Philipp Heisenberg,Y.-J. Jiang,D. A. Kane,Robert N. Kelsh,Mary C. Mullins,J. Odenthal,Rachel M. Warga,Miguel L. Allende,Eric S. Weinberg,Christiane Nüsslein-Volhard +16 more
TL;DR: In this paper, two groups of mutants with defects in this patterning process have been isolated in a screen for zygotic mutations affecting the embryonic development of the zebrafish (Danio rerio).
Journal ArticleDOI
Mutations affecting the cardiovascular system and other internal organs in zebrafish
Jau-Nian Chen,P. Haffter,J. Odenthal,Elisabeth Vogelsang,Michael Brand,F. J. M. Van Eeden,Makoto Furutani-Seiki,Michael Granato,M. Hammerschmidt,Carl-Philipp Heisenberg,Y.-J. Jiang,D. A. Kane,Robert N. Kelsh,Mary C. Mullins,Christiane Nüsslein-Volhard +14 more
TL;DR: It is demonstrated that it is feasible to screen for genes specific for the patterning or function of certain internal organs in the zebrafish and the mutations presented here could serve as an entry point to the establishment of a genetic hierarchy underlying organogenesis.
Journal ArticleDOI
Sensorimotor Gating in Larval Zebrafish
TL;DR: This work shows for the first time that the acoustic startle response in zebrafish larvae is modulated by weak prepulses in a manner similar to mammalian PPI, and reports on the first unbiased screen to identify genes regulating this process.