Radhakrishnan Venkatasamy

TL;DR: The action of fCS is supported as an inhibitor of selectin interactions, which play vital roles in inflammation and metastasis progression and future studies of f CS-selectin interaction using fCS fragments or their mimetics may open new avenues for therapeutic intervention.

TL;DR: These piperine analogues were found to increase total melanin in cell cultures, although melanin content per cell was not significantly altered from control in the presence of these compounds.

TL;DR: Piperine and its analogues have been reported to stimulate melanocyte replication in vitro and may be useful in treating the depigmenting disease, vitiligo.

TL;DR: P. nigrum, therefore, contains several amides with the ability to stimulate melanocyte proliferation and provides new lead compounds for drug development for this disease.

TL;DR: It is established that heparanase contributes to allergen-induced eosinophil recruitment to the lung and could provide a novel therapeutic target for the development of anti-inflammatory drugs for the treatment of asthma and other allergic diseases.