Rafael Andrade

TL;DR: A major subclass of human precursor T- cell neoplasms belonging to the gamma/delta T-cell receptor-rearranging subtype; a narrow repertoire of human V delta gene usage; and the utility of delta gene rearrangements as a diagnostic clonal marker in precursor T lymphoblastic neoplasm are demonstrated.

TL;DR: The authors conclude that the TCR delta gene is usually deleted in mature T-cell lymphomas, as would be expected in alpha/beta TCR T cells, however, T CR delta gene rearrangement is detectable in approximately 10% of cases.

TL;DR: A patient with a S-100-positive T-cell lymphoproliferative disorder, characterized by clinically aggressive behavior, with leukemic dissemination and death within 1 year of the onset of symptoms is described.

TL;DR: Although the preferential involvement of BCL-3 alterations in a small subset of follicular lymphomas that transform suggests a possible link between these abnormalities and progression, further studies are needed to ensure that these alterations are biologically relevant and not simply a manifestation of genomic instability.

TL;DR: A series of precursor B cell leukaemias was analysed for rearrangements at the δ chain gene locus, using probes of the variable, joining, and constant regions of the ε chain gene.