R
Rafael Valle-Oñate
Researcher at Military University Nueva Granada
Publications - 49
Citations - 694
Rafael Valle-Oñate is an academic researcher from Military University Nueva Granada. The author has contributed to research in topics: Arthritis & Ankylosing spondylitis. The author has an hindex of 14, co-authored 49 publications receiving 610 citations. Previous affiliations of Rafael Valle-Oñate include Universidad de La Sabana.
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Journal ArticleDOI
Anti-Inflammatory Effects of Sphingosine Kinase Modulation in Inflammatory Arthritis
Wen-Qi Lai,Anastasia Windy Irwan,Hong Heng Goh,Hwee Siew Howe,David T. Y. Yu,Rafael Valle-Oñate,Iain B. McInnes,Alirio J. Melendez,Bernard P. Leung +8 more
TL;DR: Results demonstrate SphK modulation may provide a novel approach in treating chronic autoimmune conditions such as RA by inhibiting the release of pro-inflammatory cytokine production in response to type II collagen in vitro.
Journal ArticleDOI
Periodontal Disease in Individuals With a Genetic Risk of Developing Arthritis and Early Rheumatoid Arthritis: A Cross-Sectional Study
Juan Manuel Bello-Gualtero,Gloria Inés Lafaurie,Lida X. Hoyos,Diana Marcela Castillo,Juliette De-Avila,Juan Carlos Munevar,Sonia Unriza,John Londoño,Rafael Valle-Oñate,Rafael Valle-Oñate,Consuelo Romero-Sánchez,Consuelo Romero-Sánchez,Consuelo Romero-Sánchez +12 more
TL;DR: This study shows that individuals with pre-RA have significant inflammatory periodontal involvement and markers of RA activity in individuals with eRA.
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Predictive validity of the ASAS classification criteria for axial and peripheral spondyloarthritis after follow-up in the ASAS cohort: a final analysis
Alexandre Sepriano,Robert Landewé,Désirée van der Heijde,Joachim Sieper,Nurullah Akkoc,J. Brandt,Jürgen Braun,Eduardo Collantes-Estevez,Maxime Dougados,Oliver FitzGerald,Feng Huang,Jieruo Gu,Yesim Kirazli,Walter P. Maksymowych,Helena Marzo-Ortega,Ignazio Olivieri,Salih Ozgocmen,Euthalia Roussou,Salvatore Scarpato,Inge Juul Sørensen,Inge Juul Sørensen,Rafael Valle-Oñate,Filip Van den Bosch,Irene E. van der Horst-Bruinsma,Ulrich Weber,James Cheng-Chung Wei,Martin Rudwaleit +26 more
TL;DR: The positive predictive value (PPV) of the baseline classification by the ASAS criteria to forecast an expert's diagnosis of ‘SpA’ after more than 4 years is excellent and the ‘imaging arm’ and ‘clinical arm” of the axSpA criteria have similar predictive validity and are truly complementary.
Journal Article
Association between Th-17 cytokine profile and clinical features in patients with spondyloarthritis.
Consuelo Romero-Sánchez,Diego Jaimes,John Londoño,J. De Avila,Jaime E. Castellanos,Juan Manuel Bello,Wilson Bautista,Rafael Valle-Oñate +7 more
TL;DR: Results suggest a possible relationship between IL-17 and enthesis involvement in SpA and higher levels of IL-23 in synovial fluid could suggest local amplification of the Th-17 cytokine profile.
Journal ArticleDOI
Identification of acute phase reactants and cytokines useful for monitoring infliximab therapy in ankylosing spondylitis.
Consuelo Romero-Sánchez,William H. Robinson,Beren H. Tomooka,John Londoño,Rafael Valle-Oñate,Feng Huang,Xiaohu Deng,Liyun Zhang,Chunhua Yang,David Tak Yan Yu +9 more
TL;DR: The results demonstrate the usefulness of using sensitivity and specificity to assess usefulness of potential biomarkers in ankylosing spondylitis patients who received three standard pulses of infliximab and found serum IL-1α was probably generated from the joint compartments.