Showing papers by "Raffaele Bruno published in 2017"
TL;DR: The trans jugular intrahepatic Porto systemic shunt (TIPS) is no longer viewed as a salvage therapy or a bridge to liver transplantation and is currently indicated for a number of conditions related to portal hypertension with positive results in survival.
102 citations
TL;DR: It is demonstrated that the adherence to a personalized, hypocaloric, low-glycaemic, low -saturated fat diet started early in pregnancy prevents GDM occurrence, in women with BMI ≥ 25 kg/m2 .
Abstract: This study aims to determine whether the prescription of a detailed lifestyle programme in overweight/obese pregnant women influences the occurrence of gestational diabetes (GDM), and if this kind of prescription increases the adherence to a healthier lifestyle in comparison to standard care. The study was designed as a randomized controlled trial, with open allocation, enrolling women at 9–12 weeks of pregnancy with a BMI ≥ 25 kg/m2. The women assigned to the Intervention group (I = 96) received a hypocaloric, low-glycaemic, low-saturated fat diet and physical activity recommendations. Those assigned to the Standard Care group (SC = 95) received lifestyle advices regarding healthy nutrition and exercise. Follow-up was planned at the 16th, 20th, 28th and 36th weeks. A total of 131 women completed the study (I = 69, SC = 62). The diet adherence was higher in the I (57.9%) than in the SC (38.7%) group. GDM occurred less frequently in the I (18.8%) than in the SC (37.1%, P = 0.019) group. The adherent women from either groups showed a lower GDM rate (12.5% vs. 41.8%, P 4000 g were significantly lower in I group. The incidence of small for gestational age babies was not different.
These findings demonstrate that the adherence to a personalized, hypocaloric, low-glycaemic, low-saturated fat diet started early in pregnancy prevents GDM occurrence, in women with BMI ≥ 25 kg/m2.
69 citations
TL;DR: Haematologic patients should be screened for hepatitis B surface antigen (HBsAg) plus anti-hepatitis B core protein (HBc), and HBV DNA before chemotherapy and immunization against HBV in patients who underwent HSCT is recommended.
63 citations
TL;DR: The findings suggest that the safety and effectiveness of ombitasvir, paritaprevir, and ritonavir, with or without dasabuvir, plus ribavirin in patients with HCV genotype 1 or 4 infection and cirrhosis at high risk of decompensation in a real-life setting are similar to those reported in clinical trials.
19 citations
University of Milan1, University of Rome Tor Vergata2, University of Palermo3, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico4, University of Padua5, University of Bologna6, University of Turin7, University of Pisa8, University of Pavia9, Humanitas University10, University of Naples Federico II11, Seconda Università degli Studi di Napoli12, University of Messina13, Sapienza University of Rome14, Regione Campania15, University of Modena and Reggio Emilia16, University of Florence17
TL;DR: To assess the Italian treatment experience with DAAs and to respond to unmet needs in treatment optimization of antiviral therapy in specific settings of CHC patients, a group of Italian experts met in Stresa in February 2017.
16 citations
TL;DR: The application of antimicrobial stewardship (AMS) rules appears to be the most appropriate strategy to globally manage cirrhotic patients with infectious complications and they represent a unique way to provide both early diagnosis and appropriate therapy.
10 citations
TL;DR: Direct-acting antivirals (DAAs) revolutionized hepatitis C virus (HCV) treatment by enabling viral eradication in more than 95% of cases across all genotypes, and two cases illustrating DAA integration in the treatment course of HCV-positive DLBCLs are reported.
10 citations
University of Pavia1, University of Paris-Sud2, Pasteur Institute3, Sapienza University of Rome4, University of Texas MD Anderson Cancer Center5, Goethe University Frankfurt6, Ospedale di Circolo e Fondazione Macchi7, Pierre-and-Marie-Curie University8, Institut de recherche pour le développement9, University of Padua10, Necker-Enfants Malades Hospital11
1 citations