Raid G. Alany

TL;DR: The barriers of the posterior eye drug delivery are discussed and the various drug-delivery strategies used to overcome these barriers are discussed.

TL;DR: A brief and simplified summary of different theories of self-assembly will be given and manufacturing methods, physical characterization techniques, bilayer membrane additives, unconventional niosomes, their recent applications as drug delivery systems, limitations and directions for future research will be discussed.

TL;DR: In this paper, the effect of cation concentration and ion valency on the mechanical, micro-structural and rheological properties of aqueous kappa (κ) and iota (ι) carrageenan dispersions were investigated using a texture analyzer, cryo-SEM and an oscillatory rheometer, respectively.

TL;DR: Water-in-oil microemulsions capable of undergoing a phase-transition to lamellar liquid crystals (LC) or bicontinuous ME upon aqueous dilution were formulated using Crodamol EO, Crill 1 and Crillet 4, an alkanol or alkanediol as cosurfactant and water to test the hypothesis that phase-Transition of ME to LC may be induced by tears and serve to prolong precorneal retention.

TL;DR: Conventional eye drops can result in poor drug bioavailability due to the unique ocular anatomy and physiology, but formulations based on gellan gum and carrageenan demonstrated a remarkable increase in viscosity, pseudoplasticity and hardness upon addition of Ca(2+) and K(+) respectively.