R
Ramandeep Rattan
Researcher at Wayne State University
Publications - 73
Citations - 3750
Ramandeep Rattan is an academic researcher from Wayne State University. The author has contributed to research in topics: Ovarian cancer & Cancer. The author has an hindex of 30, co-authored 66 publications receiving 3146 citations. Previous affiliations of Ramandeep Rattan include Sewanee: The University of the South & Medical University of South Carolina.
Papers
More filters
Journal ArticleDOI
5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside Inhibits Cancer Cell Proliferation in Vitro and in Vivo via AMP-activated Protein Kinase
TL;DR: Results indicate that AICAR can be utilized as a therapeutic drug to inhibit cancer, and AMPK can be a potential target for treatment of various cancers independent of the functional tumor suppressor gene, LKB.
Journal ArticleDOI
Effector T Cells Abrogate Stroma-Mediated Chemoresistance in Ovarian Cancer.
Weimin Wang,Ilona Kryczek,Lubomír Dostál,Heng Lin,Lijun Tan,Lili Zhao,Fujia Lu,Shuang Wei,Tomasz Maj,Dongjun Peng,Gong He,Linda Vatan,Wojciech Szeliga,Rork Kuick,Jan Kotarski,Rafał Tarkowski,Yali Dou,Ramandeep Rattan,Adnan R. Munkarah,J. Rebecca Liu,Weiping Zou +20 more
TL;DR: It is shown that fibroblasts diminish nuclear accumulation of platinum in ovarian cancer cells, resulting in resistance to platinum-based chemotherapy, and it is demonstrated that glutathione and cysteine released by fibro Blasts contribute to this resistance.
Journal ArticleDOI
Metformin suppresses ovarian cancer growth and metastasis with enhancement of cisplatin cytotoxicity in Vivo
TL;DR: The data show for the first time that, in addition to inhibiting tumor cell proliferation, metformin treatment inhibits both angiogenesis and metastatic spread of ovarian cancer.
Journal ArticleDOI
Nanoceria: A Rare-Earth Nanoparticle as a Novel Anti-Angiogenic Therapeutic Agent in Ovarian Cancer
Shailendra Giri,Ajay S. Karakoti,Rondell P. Graham,Jacie L. Maguire,Christopher M. Reilly,Sudipta Seal,Ramandeep Rattan,Viji Shridhar +7 more
TL;DR: Results indicate that cerium oxide based NCe is a novel nanoparticle that can potentially be used as an anti-angiogenic therapeutic agent in ovarian cancer.
Journal ArticleDOI
Metformin attenuates ovarian cancer cell growth in an AMP-kinase dispensable manner.
TL;DR: Evidence is provided on the role of metformin as an anti‐proliferative therapeutic that can act through both AM PK‐dependent as well as AMPK‐independent pathways.