R
Ranjit Bhardwaj
Researcher at University of Münster
Publications - 22
Citations - 3595
Ranjit Bhardwaj is an academic researcher from University of Münster. The author has contributed to research in topics: Tumor necrosis factor alpha & Proinflammatory cytokine. The author has an hindex of 19, co-authored 22 publications receiving 3516 citations.
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Journal ArticleDOI
Macrophages and angiogenesis.
TL;DR: Macrophages have the capability to influence each phase of the angiogenic process, such as alterations of the local extracellular matrix, induction of endothelial cells to migrate or proliferate, and inhibition of vascular growth with formation of differentiated capillaries.
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Proopiomelanocortin-derived peptides are synthesized and released by human keratinocytes
E Schauer,F Trautinger,A. Köck,Agatha Schwarz,Ranjit Bhardwaj,Manuel M. Simon,John C. Ansel,Thomas Schwarz,T. A. Luger +8 more
TL;DR: Evidence is provided that human keratinocytes produce POMC-derived peptides such as alpha MSH and ACTH, which have been recognized as potent immunomodulatory mediators and may have a major impact on the skin immune system.
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Macrophage-derived angiogenesis factors
TL;DR: Macrophage-derived factors that can alter this structure via degradation or via the clotting system will also be discussed, as the extracellular matrix appears to be involved in the control of angiogenesis.
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Ultraviolet-B-induced apoptosis of keratinocytes: evidence for partial involvement of tumor necrosis factor-alpha in the formation of sunburn cells.
Agatha Schwarz,Ranjit Bhardwaj,Yoshinori Aragane,Karsten Mahnke,Helge Riemann,Dieter Metze,Thomas A. Luger,Thomas Schwarz +7 more
TL;DR: In both the in vitro and in vivo systems, application of recombinant TNF-alpha alone either to untreated keratinocytes or into normal murine skin did not induce sunburn cells, which further supports the notion that UVB-induced apoptosis of keratinocyte is a multifactorial event.
Journal ArticleDOI
Calcium-dependent complex assembly of the myeloic differentiation proteins MRP-8 and MRP-14.
Stefan Teigelkamp,Ranjit Bhardwaj,Johannes Roth,G Meinardus-Hager,Michael Karas,Clemens Sorg +5 more
TL;DR: The existence of the MRP complexes in vivo was demonstrated by chemical cross-linking and subsequent isolation of complexes by immunoaffinity chromatography and the association of MRPs was shown to be Ca2+ dependent.