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Thomas Schwarz

Researcher at Boston Children's Hospital

Publications -  840
Citations -  59019

Thomas Schwarz is an academic researcher from Boston Children's Hospital. The author has contributed to research in topics: Large Hadron Collider & Higgs boson. The author has an hindex of 123, co-authored 701 publications receiving 54560 citations. Previous affiliations of Thomas Schwarz include University of Kiel & University of Nantes.

Papers
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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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The pathways of mitophagy for quality control and clearance of mitochondria.

Ghazaleh Ashrafi, +2 more
- 01 Jan 2013 - 
TL;DR: The relevance of these pathways in neurons where defects in mitophagy have been implicated in neurodegeneration are discussed, in addition to the importance of identifying specific regulators ofMitophagy that ensure selective sequestration of mitochondria as cargo.
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PINK1 and Parkin Target Miro for Phosphorylation and Degradation to Arrest Mitochondrial Motility

Xinnan Wang, +11 more
- 11 Nov 2011 - 
TL;DR: It is proposed that PINK1 phosphorylation of substrates triggers the subsequent action of Parkin and the proteasome, and the PINK/Parkin pathway may quarantine damaged mitochondria prior to their clearance.
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The mechanism of Ca2+ -dependent regulation of kinesin-mediated mitochondrial motility.

Xinnan Wang, +1 more
- 09 Jan 2009 - 
TL;DR: It is shown that kinesin is present on all axonal mitochondria, including those that are stationary or moving retrograde, and that the EF-hand motifs of Miro mediate Ca(2+)-dependent arrest of mitochondria and elucidate the regulatory mechanism.
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Combined results of searches for the standard model Higgs boson in pp collisions at √s = 7 TeV

S. Chatrchyan, +2247 more
TL;DR: In this article, the authors reported results from searches for the standard model Higgs boson in proton-proton collisions at square root(s) = 7 TeV in five decay modes: gamma pair, b-quark pair, tau lepton pair, W pair, and Z pair.