R
Raphael Lamed
Researcher at Tel Aviv University
Publications - 230
Citations - 17468
Raphael Lamed is an academic researcher from Tel Aviv University. The author has contributed to research in topics: Cellulosome & Clostridium thermocellum. The author has an hindex of 66, co-authored 230 publications receiving 16413 citations. Previous affiliations of Raphael Lamed include Yale University & Weizmann Institute of Science.
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Polysaccharide utilization by gut bacteria: potential for new insights from genomic analysis
TL;DR: Genomic analyses of the gut microbiota could revolutionize understanding of these mechanisms and provide new biotechnological tools for the conversion of polysaccharides, including lignocellulosic biomass, into monosaccharides.
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The Cellulosomes: Multienzyme Machines for Degradation of Plant Cell Wall Polysaccharides
TL;DR: The recently described three-dimensional crystal structure of the cohesin-dockerin heterodimer sheds light on the critical amino acids that contribute to this high-affinity protein-protein interaction.
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Cellulose, cellulases and cellulosomes
TL;DR: A combination of molecular genetic, biochemical, chemical, crystallographic and microscopic techniques are paving the way for new insights into both the structure of cellulose and the mechanisms of its hydrolysis.
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Characterization of a cellulose-binding, cellulase-containing complex in Clostridium thermocellum.
TL;DR: The results are consistent with the contention that the CBF comprises a discrete, multisubunit complex or group of closely related complexes which exhibit separate antigenic and multiple cellulase activities in addition to the property of cellulose binding.
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Crystal structure of a bacterial family-III cellulose-binding domain: a general mechanism for attachment to cellulose.
TL;DR: Although the proposed binding of the CBD to cellulose is essentially a surface interaction, specific types and combinations of amino acids appear to interact selectively with glucose moieties positioned on three adjacent chains of the cellulose surface.