Raphael R.S. Lopes

TL;DR: The first genome sequence of a nondipteran insect vector of an important human parasitic disease is described, which provides critical information on the physiology and evolution of this important vector species and should be instrumental for the development of innovative disease control methods.

TL;DR: The results reinforce the idea that cell lines selected in vitro may display multiple resistance strategies that may vary with the selective agent used as well as during different steps of the selection process.

TL;DR: Recent findings that not only highlight nuances in splicing pathways but also provide potential reasons for the maintenance of introns in tRNA are reviewed.

TL;DR: This work used a combination of RNA interference and molecular biology approaches to show that down-regulation of TbTrl1 expression leads to accumulation of intron-containing tRNA(Tyr) and a concomitant growth arrest at the G1 phase, while revealing tRNA splicing as its only essential function.