J
Jose Ruiz
Researcher at University of Miami
Publications - 29
Citations - 658
Jose Ruiz is an academic researcher from University of Miami. The author has contributed to research in topics: Innate immune system & TRIF. The author has an hindex of 11, co-authored 28 publications receiving 594 citations.
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Journal ArticleDOI
Differentiation stage–specific expression of microRNAs in B lymphocytes and diffuse large B-cell lymphomas
Raquel Malumbres,Kristopher A. Sarosiek,Elena Cubedo,Jose Ruiz,Xiaoyu Jiang,Randy D. Gascoyne,Robert Tibshirani,Izidore S. Lossos +7 more
TL;DR: Although an important component of the biology of a malignant cell is inherited from its nontransformed cellular progenitor-GC centroblasts-aberrant miRNA expression is acquired upon cell transformation, expression of some of the miRNAs in this signature is correlated with clinical outcome of uniformly treated DLBCL patients.
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Human intestinal epithelial cells express interleukin-10 through Toll-like receptor 4-mediated epithelial-macrophage crosstalk.
Jinhee Hyun,Laura Romero,Reldy Riveron,Claudia Flores,Saravana Kanagavelu,Kristina D. Chung,Ana Laura Alonso,John P. Sotolongo,Jose Ruiz,Armine Manukyan,Sally Chun,Gaurav Singh,Pedro Salas,Stephan R. Targan,Masayuki Fukata +14 more
TL;DR: It is suggested that TLR4 signaling maintains IL-10 production in IECs by generating epithelial-MΦs crosstalk, which is an important mechanism in the maintenance of intestinal homeostasis mediated through host-bacterial interactions.
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MUC4 and ERBB2 expression in major and minor salivary gland mucoepidermoid carcinoma.
Donald T. Weed,Carmen Gomez-Fernandez,Jeffrey Pacheco,Jose Ruiz,Kara L. Hamilton-Nelson,David Arnold,Francisco J. Civantos,Jin Zhang,Mohammed Yasin,W. Jarrard Goodwin,Kermit L. Carraway +10 more
TL;DR: This study investigates MUC4 and ErbB2 receptor expression in major and minor salivary gland mucoepidermoid carcinoma and correlates patterns of expression with clinical outcomes.
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Host innate recognition of an intestinal bacterial pathogen induces TRIF-dependent protective immunity
John P. Sotolongo,Cecilia Espana,Andrea Echeverry,David Siefker,Norman H. Altman,Julia Zaias,Rebeca Santaolalla,Jose Ruiz,Kurt Schesser,Becky Adkins,Masayuki Fukata +10 more
TL;DR: TRIF signaling triggers the amplification of macrophage bactericidal activity sufficient to eliminate invading intestinal pathogens through the sequential induction ofIFN-β and IFN-γ from macrophages and NK cells, respectively.
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Endoscopic embolization with onyx prior to resection of JNA: a new approach.
TL;DR: Although further studies are needed, it seems to provide a safe, less invasive alternative to traditional embolization and endoscopic resection, but must be done in cooperation with interventional neurosurgery to maximize its safety profile.