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Rashmi Bagga

Researcher at Post Graduate Institute of Medical Education and Research

Publications -  193
Citations -  2782

Rashmi Bagga is an academic researcher from Post Graduate Institute of Medical Education and Research. The author has contributed to research in topics: Pregnancy & Population. The author has an hindex of 24, co-authored 177 publications receiving 2216 citations.

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Mutations in NALP7 cause recurrent hydatidiform moles and reproductive wastage in humans

TL;DR: Five mutations in the maternal gene NALP7 in individuals with familial and recurrent HMs are reported, which is the first maternal effect gene identified in humans and is also responsible for recurrent spontaneous abortions, stillbirths and intrauterine growth retardation.
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Women heterozygous for NALP7/NLRP7 mutations are at risk for reproductive wastage: report of two novel mutations.

TL;DR: The data on this new family and on heterozygous women from previously reported families indicate that women heterozygously for NLRP7 mutations are at risk for reproductive wastage without the manifestation of molar phenotype, suggesting thatNLRP7 is not required for normal spermatogenesis.
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NLRP7 in the spectrum of reproductive wastage: rare non-synonymous variants confer genetic susceptibility to recurrent reproductive wastage

TL;DR: The presence of NLRP7 mutations was demonstrated in two patients with recurrent spontaneous abortions, and some rare non-synonymous variants (NSVs), present in the general population, were found to be associated with recurrent reproductive wastage.
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Obstetric morbidity and the diagnostic dilemma in pregnancy in rudimentary horn: retrospective analysis.

TL;DR: Management of pregnancy in a rudimentary uterine horn continues to be a challenge and a higher degree of alertness, especially in high risk groups by emergency staff is required to prevent the morbidity, as they may present with acute uterine rupture in pregnancy.