R
Rebecca L. Lamason
Researcher at Massachusetts Institute of Technology
Publications - 18
Citations - 1580
Rebecca L. Lamason is an academic researcher from Massachusetts Institute of Technology. The author has contributed to research in topics: Intracellular parasite & Obligate. The author has an hindex of 9, co-authored 14 publications receiving 1347 citations. Previous affiliations of Rebecca L. Lamason include University of California, Berkeley & Johns Hopkins University School of Medicine.
Papers
More filters
Journal ArticleDOI
SLC24A5, a Putative Cation Exchanger, Affects Pigmentation in Zebrafish and Humans
Rebecca L. Lamason,Manzoor Ali P.K. Mohideen,Manzoor Ali P.K. Mohideen,Jason R. Mest,Andrew C.C. Wong,Andrew C.C. Wong,Heather L. Norton,Michele C. Aros,Michael J. Jurynec,Xianyun Mao,Vanessa R. Humphreville,Jasper E. Humbert,Jasper E. Humbert,Soniya Sinha,Jessica L. Moore,Jessica L. Moore,Pudur Jagadeeswaran,Wei Zhao,Gang Ning,Izabela Makalowska,Paul M. McKeigue,David H. O'Donnell,Rick A. Kittles,Esteban J. Parra,N. J. Mangini,David Grunwald,Mark D. Shriver,Victor A. Canfield,Keith C. Cheng +28 more
TL;DR: It is shown that zebrafish golden mutants share these melanosomal changes and that golden encodes a putative cation exchanger slc24a5 (nckx5) that localizes to an intracellular membrane, likely the melanosome or its precursor.
Journal ArticleDOI
Sexual dimorphism in immune response genes as a function of puberty
Rebecca L. Lamason,Po Zhao,Rashmi Rawat,Adrian Davis,John C. Hall,Jae Jin Chae,Rajeev K. Agarwal,Phillip Cohen,Antony Rosen,Eric P. Hoffman,Kanneboyina Nagaraju +10 more
TL;DR: These results demonstrate that sexual dimorphism in innate and adaptive immune genes is dependent on puberty, and reveal that estrogen influences immunoglobulin levels in post-pubertal female mice via the Fas-FasL pathway.
Journal ArticleDOI
Rickettsia Actin-Based Motility Occurs in Distinct Phases Mediated by Different Actin Nucleators
TL;DR: It is shown that each protein directs an independent mode of Rickettsia parkeri motility at different times during infection, which may allowRickettsia to establish an intracellular niche and spread between diverse cells throughout a prolonged infection.
Journal ArticleDOI
Rickettsia Sca4 Reduces Vinculin-Mediated Intercellular Tension to Promote Spread
Rebecca L. Lamason,Effie Bastounis,Natasha M. Kafai,Ricardo Serrano,Juan C. del Álamo,Julie A. Theriot,Matthew D. Welch +6 more
TL;DR: It is suggested that surface cell antigen 4 (Sca4) relieves intercellular tension to promote protrusion engulfment, which represents a distinctive strategy for manipulating cytoskeletal force generation to enable spread.
Journal ArticleDOI
Actin-based motility and cell-to-cell spread of bacterial pathogens
TL;DR: Recent advances suggest that bacterial surface proteins exhibit divergent biochemical mechanisms of actin polymerization and recruit distinct host protein networks to drive motility, and that bacteria deploy secreted effector proteins that alter host cell mechanotransduction pathways to enable spread.