Rebecca Meißner

TL;DR: It is shown that LEEs effectively cause the reduction of the radiosensitiser nimorazole via associative electron attachment with the cross-section exceeding most of known molecules, which supports the hypothesis that nim orazole is selectively cytotoxic to tumour cells due to reduced of the molecule as prerequisite for accumulation in the cell.

TL;DR: The current study endorses OTfU as a potential radiosensitizer agent with possible applications in radio-chemotherapy.

TL;DR: It is shown that low-energy electrons very effectively decompose SeCNdU upon attachment of thermal electrons, producing a large variety of charged fragments and radicals.

TL;DR: The effects of electrons as secondary particles in the chemical degradation of histidine are demonstrated and the reactions induced by those electrons differ when comparing positive and negative ion formation.

TL;DR: Observations of the reactivity of misonidazole with low-energy electrons in a water environment combining experiment and theoretical modelling help to understand the mechanism of bio-reductive drug action.