R
Richard Heinz
Researcher at Northwestern University
Publications - 18
Citations - 466
Richard Heinz is an academic researcher from Northwestern University. The author has contributed to research in topics: Cancer research & Medicine. The author has an hindex of 6, co-authored 12 publications receiving 391 citations. Previous affiliations of Richard Heinz include Anschutz Medical Campus.
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Journal ArticleDOI
Multiple molecular subtypes of triple-negative breast cancer critically rely on androgen receptor and respond to enzalutamide in vivo.
Valerie N. Barton,Nicholas C. D'Amato,Michael A. Gordon,Hanne T. Lind,Nicole S. Spoelstra,Beatrice Babbs,Richard Heinz,Anthony D. Elias,Paul Jedlicka,Britta M. Jacobsen,Jennifer K. Richer +10 more
TL;DR: It is indicated that non-LAR subtypes of TNBC are AR dependent and, moreover, that enzalutamide is a promising targeted therapy for multiple molecular sub types of AR+ TNBC.
Journal ArticleDOI
Soy isoflavone supplementation for breast cancer risk reduction: a randomized phase II trial.
Seema A. Khan,Robert T. Chatterton,Nancy Michel,Michelle Bryk,Oukseub Lee,David Ivancic,Richard Heinz,Carola M. Zalles,Irene Helenowski,Borko Jovanovic,Adrian A. Franke,Maarten C. Bosland,Jun Wang,Nora M. Hansen,Kevin P. Bethke,Alexander Dew,Margerie Coomes,Raymond C. Bergan +17 more
TL;DR: A 6-month intervention of mixed soy isoflavones in healthy, high-risk adult Western women did not reduce breast epithelial proliferation, suggesting a lack of efficacy for breast cancer prevention and a possible adverse effect in premenopausal women.
Journal ArticleDOI
Ethanol consumption modifies dendritic cell antigen presentation in mice.
Richard Heinz,Carl Waltenbaugh +1 more
TL;DR: Ethanol alters CD11c+CD8(alpha)+ DC function, affecting cytokines responsible for adaptive immune responses, and a unifying hypothesis for the underlying mechanism(s) of ethanol's effect upon adaptive immune function is proposed.
Journal ArticleDOI
Patterns of Sex Steroid Hormones in Nipple Aspirate Fluid during the Menstrual Cycle and after Menopause in Relation to Serum Concentrations
TL;DR: This is the first description of the temporal relationships of sex steroids in NAF and serum relative to the menstrual cycle and insights into the lack of correlation of Naf and breast tissue estrogens with serum estrogens are provided, and new hypotheses are generated.
Journal ArticleDOI
Constitutive expression of microRNA-150 in mammary epithelium suppresses secretory activation and impairs de novo lipogenesis
Richard Heinz,Michael C. Rudolph,Palaniappan Ramanathan,Nicole S. Spoelstra,Kiel T. Butterfield,Patricia G. Webb,Beatrice Babbs,Hongwei Gao,Shang Chen,Michael A. Gordon,Steve M. Anderson,Margaret C. Neville,Haihua Gu,Haihua Gu,Jennifer K. Richer +14 more
TL;DR: The hypothesis that a synchronized decrease in miRNAs, such as miR-150, at late pregnancy serves to allow translation of targets crucial for lactation is supported.