R
Richard P. Dutton
Researcher at University of Chicago
Publications - 204
Citations - 8239
Richard P. Dutton is an academic researcher from University of Chicago. The author has contributed to research in topics: Medicine & Resuscitation. The author has an hindex of 44, co-authored 183 publications receiving 7368 citations. Previous affiliations of Richard P. Dutton include University of California, San Diego & University of Maryland Medical Center.
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Journal ArticleDOI
The coagulopathy of trauma: a review of mechanisms.
John R. Hess,Karim Brohi,Richard P. Dutton,Carl J. Hauser,John B. Holcomb,Yoram Kluger,Kevin Mackway-Jones,Michael Parr,Sandro Rizoli,Tetsuo Yukioka,David B. Hoyt,Bertil Bouillon +11 more
TL;DR: There is limited understanding of the mechanisms by which tissue trauma, shock, and inflammation initiate trauma coagulopathy, and Acute Coagulopathic of Trauma-Shock should be considered distinct from disseminated intravascular coagulation as described in other conditions.
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Hypotensive resuscitation during active hemorrhage: impact on in-hospital mortality.
TL;DR: Titration of initial fluid therapy to a lower than normal SBP during active hemorrhage did not affect mortality in this study, and overall mortality was decreased overall mortality and the lack of differentiation between groups likely include improvements in diagnostic and therapeutic technology.
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Blood transfusion rates in the care of acute trauma
TL;DR: This data indicates that up to 15 percent of all RBCs are used in the care of injury, and that routine resource allocation, planning for mass casualty situations, designing research, and optimizing triage all can be usefully informed.
Journal ArticleDOI
Trauma Mortality in Mature Trauma Systems: Are We Doing Better? An Analysis of Trauma Mortality Patterns, 1997-2008
Richard P. Dutton,Lynn G. Stansbury,Susan Leone,Elizabeth A. Kramer,John R. Hess,Thomas M. Scalea +5 more
TL;DR: Survival after severe trauma and survival benchmarked against predicted risk improved significantly at a mature trauma system during the past 12 years despite generally increasing age and worsening injuries.
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Results of the CONTROL trial: efficacy and safety of recombinant activated Factor VII in the management of refractory traumatic hemorrhage.
Carl J. Hauser,Kenneth D. Boffard,Richard P. Dutton,Gordon R. Bernard,Martin A. Croce,John B. Holcomb,Ari Leppäniemi,Michael Parr,Jean Louis Vincent,Bartholomew J. Tortella,Jeannett Dimsits,Bertil Bouillon +11 more
TL;DR: Recombinant Factor VIIa reduced blood product use but did not affect mortality compared with placebo, paradoxically making outcomes studies increasingly difficult.