R
Richard S. Trompeter
Researcher at University College London
Publications - 65
Citations - 3115
Richard S. Trompeter is an academic researcher from University College London. The author has contributed to research in topics: Transplantation & Nephrotic syndrome. The author has an hindex of 31, co-authored 64 publications receiving 2842 citations. Previous affiliations of Richard S. Trompeter include Great Ormond Street Hospital for Children NHS Foundation Trust & Great Ormond Street Hospital.
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Journal ArticleDOI
HNF1B Mutations Associate with Hypomagnesemia and Renal Magnesium Wasting
Shazia Adalat,Adrian S. Woolf,Karen A. Johnstone,A. Wirsing,Lorna W. Harries,David A. Long,Raoul C.M. Hennekam,Sarah Ledermann,Lesley Rees,William van’t Hoff,Stephen D. Marks,Richard S. Trompeter,Kjell Tullus,Paul J.D. Winyard,Janette Cansick,Imran Mushtaq,Harjeeta K. Dhillon,Coralie Bingham,Emma L. Edghill,Rukshana Shroff,Horia Stanescu,Gerhart U. Ryffel,Sian Ellard,Detlef Bockenhauer +23 more
TL;DR: A role for HNF1B not only in nephrogenesis but also in the maintenance of tubular function is described, thus describing a role for a transcription factor expressed in tissues including renal epithelia and regulating transcription of FXYD2 in the tubular handling of Mg(2+).
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Autosomal recessive polycystic kidney disease: long-term outcome of neonatal survivors
TL;DR: The study indicates a relatively good prognosis for patients with this condition who survive the neonatal period and emphasises the importance of early detection and appropriate management of systemic and portal hypertension.
Journal ArticleDOI
A randomized trial to assess the impact of early steroid withdrawal on growth in pediatric renal transplantation: the TWIST study
Ryszard Grenda,Alan R. Watson,Richard S. Trompeter,Burkhard Tönshoff,Jeno Járay,M. Fitzpatrick,Luisa Murer,Karel Vondrak,Heather Maxwell,R. Van Damme-Lombaerts,Chantal Loirat,Eytan Mor,Pierre Cochat,David V. Milford,M. Brown,Nicholas J. A. Webb +15 more
TL;DR: Early steroid withdrawal significantly aided growth at 6 months more so in prepubertal than pubertal children and was accompanied by significantly better lipid and glucose metabolism profiles without increases in graft rejection or loss.
Journal ArticleDOI
Long-term outcome of peritoneal dialysis in infants.
Sarah Ledermann,Maria E. Scanes,Oswald N. Fernando,Patrick G. Duffy,Shelagh J. Madden,Richard S. Trompeter +5 more
TL;DR: Peritoneal dialysis in infancy is a demanding treatment, but outcome for growth, development, and transplantation justifies this intensive approach.
Journal ArticleDOI
Interleukin-8 and polymorphoneutrophil leucocyte activation in hemolytic uremic syndrome of childhood.
Margaret M. Fitzpatrick,Vanita Shah,Richard S. Trompeter,Michael J. Dillon,T. Martin Barratt +4 more
TL;DR: The data suggest that PMNLs in HUS are recruited by IL-8, that this cytokine plays a key role in the PMNL activation which occurs, and that agents which suppress this recruitment and activation might play a therapeutic role in this disorder.