Robert Heymann

TL;DR: Support for the replacement hypothesis was obtained from experiments in which the extracellular signal-regulated kinases (Erk)1/2 were activated by anti-CEACAM Abs and it was demonstrated that CEACAM1 and CEACam8 are physically associated in human granulocytes.

TL;DR: Oral mucosal MAIT cells form a part of the oral mucosal T cell compartment, where they exhibit a tissue‐resident‐activated profile biased toward IL‐17 production, as assessed by polyclonal stimulus and compared to tissue nonresident and circulating populations.

TL;DR: Results suggest that E- and N-cadherins may play a role during human tooth development and indicate that N- cadherin is important for odontoblast function in normal development and under pathological conditions.

TL;DR: CEACAM1 can exert its signal‐regulating activities by discriminating between binding of Src kinases and SHP phosphatases, respectively, and major factors that regulate this discrimination are the expression levels and expression ratios of transmembrane CEACam1‐L and CEACAM2‐S, and homophilic binding of CEAC AM1 presented by neighboring cells.

TL;DR: The results indicate that the characteristic morphology and the high expression levels of CEACAM1 in the junctional epithelium are genetically programmed and not a result of bacterial infiltration, which suggests that CEACam1 has an important role for the structural integrity of the junctionAL epithelia.