J
Johan K. Sandberg
Researcher at Karolinska University Hospital
Publications - 199
Citations - 9851
Johan K. Sandberg is an academic researcher from Karolinska University Hospital. The author has contributed to research in topics: Immune system & T cell. The author has an hindex of 51, co-authored 194 publications receiving 7844 citations. Previous affiliations of Johan K. Sandberg include Karolinska Institutet & Aaron Diamond AIDS Research Center.
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Journal ArticleDOI
Robust T Cell Immunity in Convalescent Individuals with Asymptomatic or Mild COVID-19.
Takuya Sekine,André Perez-Potti,Olga Rivera-Ballesteros,Kristoffer Strålin,Jean Baptiste Gorin,Annika Olsson,Sian Llewellyn-Lacey,Habiba Kamal,Gordana Bogdanovic,Sandra Muschiol,David J. Wullimann,Tobias Kammann,Johanna Emgård,Tiphaine Parrot,Elin Folkesson,Olav Rooyackers,Lars Eriksson,Jan-Inge Henter,Anders Sönnerborg,Tobias Allander,Jan Albert,Morten Nielsen,Jonas Klingström,Sara Gredmark-Russ,Niklas K. Björkström,Johan K. Sandberg,David Price,Hans-Gustaf Ljunggren,Soo Aleman,Marcus Buggert +29 more
TL;DR: It is shown that SARS-CoV-2 elicits robust, broad and highly functional memory T cell responses, suggesting that natural exposure or infection may prevent recurrent episodes of severe COVID-19.
Journal ArticleDOI
Activation, exhaustion, and persistent decline of the antimicrobial MR1-restricted MAIT-cell population in chronic HIV-1 infection
Edwin Leeansyah,Anupama Ganesh,Máire F. Quigley,Anders Sönnerborg,Jan Andersson,Peter W. Hunt,Ma Somsouk,Steven G. Deeks,Jeffrey N. Martin,Markus Moll,Barbara L. Shacklett,Johan K. Sandberg +11 more
TL;DR: Interestingly, MAIT cells in rectal mucosa were relatively preserved, although some of the changes seen in blood were recapitulated in the mucosa, consistent with a model in which the MAIT-cell compartment is engaged, activated, exhausted, and progressively and persistently depleted during chronic HIV-1 infection.
Journal ArticleDOI
Natural killer cell immunotypes related to COVID-19 disease severity.
Christopher Maucourant,Iva Filipovic,Andrea Ponzetta,Soo Aleman,Soo Aleman,Martin Cornillet,Laura Hertwig,Benedikt Strunz,Antonio Lentini,Björn Reinius,Demi Brownlie,Angelica Cuapio,Eivind Heggernes Ask,Eivind Heggernes Ask,Ryan M. Hull,Alvaro Haroun-Izquierdo,Marie Schaffer,Jonas Klingström,Elin Folkesson,Elin Folkesson,Marcus Buggert,Johan K. Sandberg,Lars Eriksson,Lars Eriksson,Olav Rooyackers,Olav Rooyackers,Hans-Gustaf Ljunggren,Karl-Johan Malmberg,Karl-Johan Malmberg,Karl-Johan Malmberg,Jakob Michaëlsson,Nicole Marquardt,Quirin Hammer,Kristoffer Strålin,Kristoffer Strålin,Niklas K. Björkström +35 more
TL;DR: The NK cell activation landscape in acute SARS-CoV-2 infection is associated with COVID-19 disease severity, and arming of CD56bright NK cells was observed across COIDs disease states, driven by a defined protein-protein interaction network of inflammatory soluble factors.
Journal ArticleDOI
CD56 negative NK cells: origin, function, and role in chronic viral disease.
TL;DR: Current knowledge of CD56(neg) NK cells is discussed, with a particular emphasis on their accumulation during chronic infection and the possible consequences of this for the host.
Posted ContentDOI
Robust T cell immunity in convalescent individuals with asymptomatic or mild COVID-19
Takuya Sekine,André Perez-Potti,Olga Rivera-Ballesteros,Kristoffer Strålin,Jean-Baptiste Gorin,Annika Olsson,Sian Llewellyn-Lacey,Habiba Kamal,Gordana Bogdanovic,Sandra Muschiol,David J. Wullimann,Tobias Kammann,Johanna Emgård,Tiphaine Parrot,Elin Folkesson,Olav Rooyackers,Olav Rooyackers,Lars Eriksson,Lars Eriksson,Anders Sönnerborg,Tobias Allander,Tobias Allander,Jan Albert,Jan Albert,Morten Nielsen,Jonas Klingström,Sara Gredmark-Russ,Niklas K. Björkström,Johan K. Sandberg,David Price,Hans-Gustaf Ljunggren,Soo Aleman,Marcus Buggert +32 more
TL;DR: The collective dataset shows that SARS-CoV-2 elicits robust memory T cell responses akin to those observed in the context of successful vaccines, suggesting that natural exposure or infection may prevent recurrent episodes of severe COVID-19 also in seronegative individuals.