Robert Huber

TL;DR: A novel method and the associated instrumentation for improving crystalline order (higher resolution of X-ray diffraction and reduced mosaicity) of protein crystals by precisely controlled heating is demonstrated.

TL;DR: In this article, a bivalent proteasome inhibitor compound comprising two head groups and a spacer linking the two heads groups was proposed, wherein the two head group can be the same or different and are each capable of inhibiting one or more active sites of the proteasomes and the spacer comprises a flexible, substantially linear organic compound with a length of 25 A to 100 A.

TL;DR: The crystal structure of the aldehyde oxidoreductase (Mop) from the sulphate-reducing bacterium Destdjovibrio gigas has been analysed and refined to 1.8A (0.18 nm) resolution, allowing a detailed look at several structural aspects relevant to catalysis.

TL;DR: Proteins perform many different functions in the living organism: enzymes are catalysts, hormones are messengers in regulatory processes, immune proteins recognize, bind and, after a multi-step process, eliminate foreign molecules and cells.

TL;DR: In this paper, an analytical expression for molecular overlap as a function of position is presented; it can be calculated by means of Fourier transforms and can be combined to give a crystallographic packing function.