Robert L. Martuza

TL;DR: These data demonstrate that at least 2 contributions to glioma cellular architecture exist: genetic influences, as identified by mutation and chromosomal aberrations within tumor subclones, and nongenetic influences whereby progenitor-like tumor cells give rise to 2 dominant, more differentiated glial subpopulations of tumor cells, in a process akin to normal differentiation during neurodevelopment.

TL;DR: Increased number of atypical features, mitoses ≥4 per 10 high-power fields, subtotal resection, and lack of adjuvant radiotherapy were independently associated with progression/recurrence of WHO Grade I-II meningiomas.

TL;DR: The distinct clinical and genetic features of NF-2 are reviewed in the context of recent data that show it to be a disorder distinct from classic von Recklinghausen's disease (NF-1).

TL;DR: Microsurgery via the suboccipital approach is a common treatment option for vestibular schwannomas (VS) and the internal auditory canal is drilled and dissection of the tumor progresses.

TL;DR: It is discussed is that local viral expression of cytokines could overcome the immunosuppressive tumor microenvironment and lead to tumor clearance including immune clearance of distant noninfected tumor cells.