Robert P. Hasserjian

TL;DR: Patients with Ph+ AML were less likely to have splenomegaly or peripheral basophilia and had lower bone marrow cellularity and myeloid/erythroid ratios than patients with CML-MBC and additional specific cytogenetic abnormalities that typically occur in CML -MBC were less common in Ph+AML.

TL;DR: Analysis of patterns of expression of NOTCH1 protein in thymocytes of the developing and mature thymus and flow cytometric analysis and immunohistochemical staining of flow-sorted cells indicate a dynamic pattern of Notch1 expression during T-cell differentiation and suggest that downregulation of NOTch1 may be required for maturation of cortical thymocyte.

TL;DR: Findings indicate that, in contrast to adult follicular lymphomas, dysregulated bcl-2 expression does not play a significant pathogenetic role in most pediatric follicularymphoma, however, bcl -2 expression in pediatric follicle lymphoma identifies a subset of patients in whom disease is often disseminated at clinical presentation and is more refractory to combination chemotherapy.

TL;DR: In this article, the authors performed shotgun DNA sequencing on four archived, paraffin-embedded endoscopic colon-biopsy specimens obtained from two patients with cord colitis.

TL;DR: It is concluded that the panenteritis associated with injection of α-CTLA-4 mAbs demonstrates histology resembling autoimmune enteropathy, and it is suspected that the increased number of regulatory T cells in the gastrointestinal mucosa may play a role in the pathogenicity.