Robert S. Hudson

TL;DR: Significant differences in microRNA abundance were found between organ-confined tumors and those with extraprostatic disease extension, and evidence that some microRNAs are androgen-regulated and that tumor micro RNAs influence transcript abundance of protein-coding target genes in the cancerous prostate was found.

TL;DR: NOS2 is associated with a basal-like transcription pattern and poor survival of ER-negative patients, and pathway analysis linked the tumor NOS2 gene signature to c-Myc activation.

TL;DR: A large number of studies have investigated the molecular differences between prostate tumors with PNI and those without it, and found that PNI is the dominant pathway for local invasion in prostate cancer.

TL;DR: The findings indicate that miR-1 acts as a tumor suppressor in prostate cancer by influencing multiple cancer-related processes and by inhibiting cell proliferation and motility.

TL;DR: The miR-106b-25 microRNA (miRNA) cluster is a candidate oncogene in human prostate cancer as discussed by the authors and miRNAs encoded by miR106b25 are upregulated in both primary tumors and distant metastasis.